Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
A Visual Question Answering Dataset for Benchmarking Vision-Language Models in Plant Science. [PDF]
Sakib SN, Haque N, Hossain MZ, Arman SE.
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Smartphone-Based Automated Quantification of Bulbar Conjunctival Hyperemia Using Vessel Density Mapping. [PDF]
Rubegni G +9 more
europepmc +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Association of posterior occlusal support with ultrasonographic characteristics of the masseter muscle: a prospective single-center study. [PDF]
Tekin A +3 more
europepmc +1 more source
Detection-Guided ROI-Constrained Diffusion for Weakly Supervised White Blood Cell Segmentation: A Retrospective Internal and External Dataset Evaluation. [PDF]
Bamwenda J +4 more
europepmc +1 more source
Ultrasound Archiving in the Emergency Department: Implementation, Governance and 4-Year Outcomes at an Australian Tertiary Emergency Department. [PDF]
Manivel V +3 more
europepmc +1 more source
CT-Based Radiomics in Renal Tumors: Current Evidence, Methodological Challenges, and Future Perspectives for Precision Oncology. [PDF]
Colarieti A +3 more
europepmc +1 more source
Accuracy of the registration of a digital dental cast or intraoral scan into a stereophotogrammetric image of the face: a systematic review. [PDF]
Go AEHC +4 more
europepmc +1 more source

