A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Advanced Experimental Technology, Theory and Numerical Methods in Geomaterials and Concrete Materials. [PDF]
Sun W, Li Y, Liu R, Yu S.
europepmc +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Verification of the Applicability of the FAD Method Based on Full-Scale Pressurised Tensile Tests of Large-Diameter X80 Pipelines. [PDF]
Chen X +7 more
europepmc +1 more source
Hover and forward flight acoustics and performance of a small-scale helicopter rotor system [PDF]
A 2.1-m diam., 1/6-scale model helicopter main rotor was tested in hover in the test section of the NASA Ames 40- by 80- Foot Wind Tunnel. Subsequently, it was tested in forward flight in the Ames 7- by 10-Foot Wind Tunnel.
Kitaplioglu, C., Shinoda, P.
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Author Correction: Regional biodiversity monitoring reveals severe population decline of the Atlantic horseshoe crab (Limulus polyphemus) in Long Island Sound, USA. [PDF]
Crosby SC +5 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The ERIES-BOLT project: Behaviour of Telecommunication Lattice Towers under Thunderstorm Winds. [PDF]
Calotescu I +5 more
europepmc +1 more source

