Results 71 to 80 of about 57,547 (250)
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Outage performance of multi-relay collaborative NOMA systems supporting multiple multicast services
Dianxin kexue, 2023 A cooperative non-orthogonal multiple access (NOMA) system was proposed to support unicast primary user and multiple multicast services based on multiple relays strategy.Under the Rayleigh channel, the secondary user with the best channel condition from ...
Yifei CHU, Xinjie YANG
doaj +2 more sources
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Novel Cancellation Techniques and Throughput Analysis for 6G Full-Duplex Wireless System
Space: Science & TechnologyRecent researches show that it is possible to achieve full-duplex system if the self-interference signal could be cancelled completely for 6G research. The majority of the overall self-interference cancellation is contributed by passive cancellation. The
Di Wu +6 more
doaj +1 more source
Machine Learning of Temperature‐Dependent Chemical Kinetics Using Parallel Droplet Microreactors
Advanced Science, EarlyView.An integrated droplet microfluidics and machine learning framework enables high‐throughput characterization of temperature‐dependent reaction kinetics. Time‐resolved measurements from thousands of droplets train Neural ODE models that accurately predict nonlinear reaction dynamics across diverse thermal environments, bridging large‐scale ...
Mamoru Saita, Yutaka Hori
wiley +1 more source
Engineering ReportsCoding metasurfaces have the advantage of controlling electromagnetic waves by designing digital states of the unit elements. This digital mechanism can be conveniently integrated into electronic information systems, hence, coding metasurfaces have been ...
Jia Chen Wan +3 more
doaj +1 more source
Link selection based on switching between full‐duplex and half‐duplex modes
ETRI Journal, 2019 Multiple‐input multiple‐output systems can achieve a full sum rate (SR) via full duplex (FD). However, its performance is degraded by self‐interference (SI) that occurs between the transmitter and receiver at the same node and thus is constrained by ...
Sangchoon Kim
doaj +1 more source
Advanced Science, EarlyView.Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang +14 more
wiley +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Advanced Science, EarlyView.Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
Advanced Science, EarlyView.A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source