Results 81 to 90 of about 217,874 (273)

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Analysis of Statistical QoS in Half Duplex and Full Duplex Dense Heterogeneous Cellular Networks [PDF]

, 2017
Statistical QoS provisioning as an important performance metric in analyzing next generation mobile cellular network, aka 5G, is investigated. In this context, by quantifying the performance in terms of the effective capacity, we introduce a lower bound ...
Lahouti, Farshad, Luvisotto, Michele, Sadeghi, Alireza, Zorzi, Michele   +3 more
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Photonic Time Crystals and Time‐Varying Electromagnetic Metamatter: A New Direction for Ultrafast Tunable Photonic and Microwave Materials and Devices

Advanced Science, EarlyView.
Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel, Shriram Ramanathan, Ronald P. Jenkins, Michael J. Carter   +3 more
wiley   +1 more source

Outage performance of multi-relay collaborative NOMA systems supporting multiple multicast services

Dianxin kexue, 2023
A cooperative non-orthogonal multiple access (NOMA) system was proposed to support unicast primary user and multiple multicast services based on multiple relays strategy.Under the Rayleigh channel, the secondary user with the best channel condition from ...
Yifei CHU, Xinjie YANG
doaj   +2 more sources

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Using a Binary Coding Metasurface to Achieve Polarization‐Dependent Full‐Duplex and Full‐Polarization Receiving

Engineering Reports
Coding metasurfaces have the advantage of controlling electromagnetic waves by designing digital states of the unit elements. This digital mechanism can be conveniently integrated into electronic information systems, hence, coding metasurfaces have been ...
Jia Chen Wan, Jia Wei Wang, Xu Jie Wang, Xiang Wan   +3 more
doaj   +1 more source

Novel Cancellation Techniques and Throughput Analysis for 6G Full-Duplex Wireless System

Space: Science & Technology
Recent researches show that it is possible to achieve full-duplex system if the self-interference signal could be cancelled completely for 6G research. The majority of the overall self-interference cancellation is contributed by passive cancellation. The
Di Wu, Jingyao Wang, Yifei Zhang, Dunwei Du, Ziwei Wan, Li Qiao, Tong Qin   +6 more
doaj   +1 more source

Multi-Antenna Cooperative Wireless Systems: A Diversity-Multiplexing Tradeoff Perspective

, 2007
We consider a general multiple antenna network with multiple sources, multiple destinations and multiple relays in terms of the diversity-multiplexing tradeoff (DMT).
Erkip, Elza, Yuksel, Melda
core   +1 more source