Results 161 to 170 of about 16,868 (267)

An integrated case-based leptospirosis surveillance dataset with environmental context from a tropical coastal city in Indonesia, 2018-2023. [PDF]

Data Brief
Adhinugraha K, Ciptaningtyas VR, Hapsari R, Wisudiawan GAA, Lestari WD, Hutapea JBMP, Pakpahan SB, Taniar D.   +7 more
europepmc   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

The Dementias Platform UK PET/MR harmonisation and test-retest study: assessment of PET repeatability and reproducibility across the national network. [PDF]

Eur J Nucl Med Mol Imaging
Markiewicz PJ, Thompson G, Wardlaw JM, Wimberley C, Ritchie C, Taylor JP, Brooks D, Maxwell R, Firbank M, Hoggard N, Su L, Wild J, Hillel P, Rhodes-Bradford V, Parkes LM, O'Brien JT, Carter SF, Aigbirhio FI, Fryer T, Matthews PM, Malhotra P, Grey G, Hallett W, Ocal D, Dickson JC, De Vita E, Thomas DL, Fox NC, Krokos G, Mackewn JE, Marsden P, Hammers A, Herholz K, Barkhof F, Matthews JC.   +34 more
europepmc   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

Multi-Omics for Mothers and Infants (MOMI) Consortium: a global initiative to study adverse pregnancy outcomes. [PDF]

J Glob Health
Tang X, Ahmed S, Ahmed FB, Albrecht V, Brennsteiner V, Chang AL, Chowdhury NH, Deb S, Gormley M, Hasan T, Kamulaza L, Khalid J, Khan W, Khanam R, Kshetrapal P, Luo H, Maiti TK, Maitra A, Mannan MM, Mueller-Reif J, Mulenga C, Nisar I, Pervin J, Pokaprakarn T, Price J, Qazi MF, Rittenhouse K, Sebastiao Y, Sindano N, Sinha T, Sopory S, Steger M, Thiruvengadam R, Wadhwa N, Xue L, Aghaeepour N, Baqui AH, Bhatnagar S, Fisher S, Fox M, Hampel D, Kasaro M, Mann M, Rahman A, Sazawal S, Shenhav L, Stringer JS, Zhang G, Jehan F, De Paris K.   +49 more
europepmc   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

Advanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Explainable machine learning of PROGRESS-Plus social factors predicts cognitive trajectories after traumatic brain injury. [PDF]

Sci Rep
Xu J, Shaikh U, Tylinski Sant'Ana T, Mollayeva T.   +3 more
europepmc   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

Methodological adaptations for applying the Harmonised Cognitive Assessment Protocol diagnostic algorithm in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA-HCAP). [PDF]

BMC Res Notes
Ward NA, Marr C, Simoes S, O'Hara L, McAlinden M, Sterling C, Potter C, Kee F, Passmore P, Scott A, Weir DR, McGuinness B.   +11 more
europepmc   +1 more source

A Sustainable Bio‐Based Epoxy Thermoset as a High‐Performance Alternative to BPA‐Based Resins

Advanced Science, EarlyView.
A rigid–flexible bio‐based epoxy network integrates soybean oil, lignin, and maleic anhydride to overcome the strength–toughness–sustainability trade‐off of conventional BPA epoxy. The thermoset delivers excellent performance as both a structural adhesive and a matrix for glass‐fabric composites, while enabling pH‐responsive degradation, environmental ...
Jiyun Qi, Xinyi Hui, Xipeng Zhang, Jia‐Long Wen, Tong‐Qi Yuan   +4 more
wiley   +1 more source