Results 51 to 60 of about 9,226,030 (253)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Full Issue

open access: yes, 2021
Full ...
Full Issue, Full Issue
core   +1 more source

On entropy-constrained Gaussian channel capacity via the moment problem

open access: yes
We study the capacity of the power-constrained additive Gaussian channel with an entropy constraint at the input. In particular, we characterize this capacity in the low signal-to-noise ratio regime, as a corollary of the following general result on a ...
Shamai, Shlomo   +2 more
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Equilibrium and stability of beams with elastoplastic semi-rigid joints [PDF]

open access: yesArchives of Civil Engineering
The classical theory of beams admits two types of connections between structural elements: perfectly rigid and perfectly flexible. However, the engineering reality calls for a more general approach to joint modelling.
Grzegorz Dzierżanowski
doaj   +1 more source

Robust and Adaptive Path-Following Control of an Underactuated Ship

open access: yesIEEE Access, 2020
The design of a vessel path-following control system based on a full, realistic, nonlinear model is considered. The control objective is to force a surface, course-unstable vessel to track a predefined geometric path.
Zenon Zwierzewicz
doaj   +1 more source

The Sobolev-type moment problem [PDF]

open access: yes, 2000
9 pages, no figures.-- MSC2000 codes: Primary 44A99; Secondary 47B15, 47B20, 47B25.MR#: MR1694873 (2000k:44006)Zbl#: Zbl 0951.44002We propose necessary and sufficient conditions for a bisequence of complex numbers to be a moment one of Sobolev type over ...
Szafraniec, Franciszek H.   +1 more
core   +2 more sources

Resolution of the finite Markov moment problem [PDF]

open access: yes, 2005
International audienceWe expose in full detail a constructive procedure to invert the so--called ``finite Markov moment problem".
Olof Runborg   +5 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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