Results 51 to 60 of about 1,704,825 (163)

Full-reference calibration-free image quality assessment

open access: yesSignal Processing: Image Communication
One major problem of objective Image Quality Assessment (IQA) methods is the lack of linearity of their quality estimates with respect to scores expressed by human subjects. For this reason, usually IQA metrics undergo a calibration process based on subjective quality examples. However, example-based training makes generalization problematic, hampering
Paolo Giannitrapani   +2 more
openaire   +2 more sources

Thrombin Generation in Acute and Chronic Liver Disease in Children

open access: yesDiagnostics
Background: Pediatric liver disease is frequently associated with abnormal conventional coagulation tests; however, prothrombin time expressed as international normalized ratio (PT-INR) incompletely reflect global hemostatic balance.
Giovina Di Felice   +11 more
doaj   +1 more source

Is highly purified cannabidiol a treatment opportunity for drug‐resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?

open access: yesEpilepsia Open
Objective This study aimed to evaluate the efficacy and safety of adjunctive, highly purified Cannabidiol (Epidiolex®) in individuals with drug‐resistant epilepsy (DRE) due to genetically determined typical Rett Syndrome (RTT) and CDKL5 Deficiency ...
Aglaia Vignoli   +22 more
doaj   +1 more source

Molecular mechanisms underlying the ferroptosis-induced epileptiform activity in mouse cortical slices

open access: yesFrontiers in Cellular Neuroscience
IntroductionFerroptosis, a newly defined iron-dependent programmed cell death, characterized by excessive accumulation of lipid peroxides and reactive oxygen species, is involved in epilepsy, particularly in those forms resistant to drugs.
Sara Petrillo   +12 more
doaj   +1 more source

Altered cytoskeleton dynamics in patient-derived iPSC-based model of PCDH19 clustering epilepsy

open access: yesFrontiers in Cell and Developmental Biology
Protocadherin 19 (PCDH19) is an adhesion molecule involved in cell-cell interaction whose mutations cause a drug-resistant form of epilepsy, named PCDH19-Clustering Epilepsy (PCDH19-CE, MIM 300088).
Rossella Borghi   +8 more
doaj   +1 more source

Morphometric network-based abnormalities correlate with psychiatric comorbidities and gene expression in PCDH19-related developmental and epileptic encephalopathy

open access: yesTranslational Psychiatry
Protocadherin-19 (PCDH19) developmental and epileptic encephalopathy causes an early-onset epilepsy syndrome with limbic seizures, typically occurring in clusters and variably associated with intellectual disability and a range of psychiatric disorders ...
Matteo Lenge   +16 more
doaj   +1 more source

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