ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Aptamer-Conjugated PEGylated Quantum Dots Targeting Epidermal Growth Factor Receptor Variant III for Fluorescence Imaging of Glioma [Retraction]. [PDF]
europepmc +1 more source
Light-emitting polymer semiconductors in flexible electronics: strategies, challenges and future perspective. [PDF]
An X +8 more
europepmc +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
A Facile Strategy for 3'-Terminal Functionalization of DNA and RNA via On-Column Conjugation with Integration into Tandem Oligonucleotide Synthesis. [PDF]
Saraya JS, O'Flaherty DK.
europepmc +1 more source
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Impact of ripening on the distribution of jackfruit polyphenol fractions and their inhibitory activities against metabolic enzymes. [PDF]
Ma L +7 more
europepmc +1 more source
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
Mitochondrial oxidative stress promotes the accumulation of advanced glycation end products. [PDF]
Akhter F +6 more
europepmc +1 more source
Tuneable emission from disordered to ordered aggregates in substituted 9,10-dihydroanthracene polymers. [PDF]
Woering EF +4 more
europepmc +1 more source

