Results 61 to 70 of about 3,274 (204)

Dual RNA sequencing of Vitis vinifera during Lasiodiplodia theobromae infection unveils host-pathogen interactions [PDF]

, 2019
Lasiodiplodia theobromae is one of the most aggressive agents of the grapevine trunk disease Botryosphaeria dieback. Through a dual RNA-sequencing approach, this study aimed to give a broader perspective on the infection strategy deployed by L ...
Alves, Artur, Deforce, Dieter, Esteves, Ana C, Gonçalves, Micael FM, Nunes, Rui B, Tilleman, Laurentijn, Van de Peer, Yves, Van Nieuwerburgh, Filip   +7 more
core   +4 more sources

Therapeutic Monitoring of Patients With Hereditary Tyrosinemia Type 1-A Belgian Monocentric Experience. [PDF]

JIMD Rep
ABSTRACT Hereditary tyrosinemia type I (HT‐1) is a rare metabolic disorder treated by NTBC, requiring careful therapeutic and nutritional monitoring. While follow‐up traditionally relies on urinary succinylacetone, plasma NTBC and plasma amino acids, dried blood spot (DBS) methods have introduced alternative monitoring options.
Adam AS, Marcélis L, Fage D, Mathieu E, Empain A, Dufour C, Cotton F, de Laet C.   +7 more
europepmc   +2 more sources

Hepatitis C virus infection and related liver disease: the quest for the best animal model [PDF]

, 2013
Hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma (HCC) making the virus the most common cause of liver failure and transplantation.
Baumert, Thomas F, Mailly, Laurent, Meuleman, Philip, Robinet, Eric, Zeisel, Mirjam   +4 more
core   +3 more sources

Contribution of human hematopoietic stem cells to liver repair [PDF]

, 2009
Immune-deficient mouse models of liver damage allow examination of human stem cell migration to sites of damage and subsequent contribution to repair and survival.
Ping Zhou, Louisa Wirthlin, Jeannine McGee, Geralyn Annett, Jan Nolta, AJ Wagers, JE Grove, AJ Wagers, E Lagasse, LB Balsam, JM Nygren, CE Murry, D Orlic, KI Park, D Hess, N Terada, G Vassilopoulos, X Wang, SY Corbel, M Alvarez-Dolado, H Willenbring, A Ianus, RG Harris, P Zhou, R Botta, SS Thorgeirsson, K Kashofer, P Zhou, MA Goodell, MA Goodell, M Bhatia, MA Dao, MA Dao, MA Dao, T Sato, DA Hess, MA Dao, ED Zanjani, RW Storms, J Cai, P Fallon, RW Storms, DA Hess, P Lang, N Forraz, W Wagner, K Ruzicka, M Bhatia, DA Hess, BJ Capoccia, M Bhargava, KM Weidner, EM Rosen, C Gao, HS Lee, DP Bottaro, K Mizuno, F Galimi, T Nishino, S Ikehara, MZ Ratajczak, CZ Yu, T Iguchi, IS Weimar, JP Goff, IDGaEM Rosen, T Nakamura, E Sonnenberg, S Noji, J Fujimoto, S Yasuda, T Sato, SM Sheehan, GH Danet, DJ Ceradini, ST Avecilla, I Rosova, S Pennacchietti, QL Hao, QL Hao, QL Hao, AJ Shah, QL Hao, X Wang, MA Dao, JA Nolta, E Tsark, AA Hofling, DA Hess, FD Camargo, YY Jang, M Muraca, FD Camargo, AD Sharma, H Fujino, N Selzner, N Fausto, I Sakaida   +97 more
core   +2 more sources

An Unusual Presentation of Tyrosinemia Type 1 in a Pediatric Patient: Case Report and Comprehensive Review. [PDF]

Clin Case Rep
ABSTRACT Tyrosinemia type 1 often manifests with liver, renal, or peripheral neuropathy disorders. Before therapies like nitisinone, management was limited to dietary modifications and liver transplantation. We present a 19‐month‐old girl who developed respiratory distress requiring intubation, with abnormal laboratory findings, including liver ...
Rouhafshari M, Hadi Imanieh M, Khazaei M, Radaei Z, Barzegar H.   +4 more
europepmc   +2 more sources

Effect of ligands to toll-like receptors (TLR) 3, 7 and 9 on mice infected with mouse hepatitis virus A59 [PDF]

, 2014
Mice infected with mouse hepatitis virus A59 (MHV-A59), an enveloped, positive-strand RNA Co-ronavirus, induce hepatitis, thymus involution, IgG2a-restricted hypergammaglobulinaemia, transaminase release and autoantibodies (autoAb) to liver and kidney ...
Aparicio, Jose Luis, Duhalde Vega, Maite, Retegui, Lilia Alicia   +2 more
core   +1 more source

Animal models to study hepatitis C virus infection [PDF]

, 2018
With more than 71 million chronically infected people, the hepatitis C virus (HCV) is a major global health concern. Although new direct acting antivirals have significantly improved the rate of HCV cure, high therapy cost, potential emergence of drug ...
Ahmed Atef Mesalam, Ahmed Atef Mesalam, Laura Collignon, Philip Meuleman, Rani Burm   +4 more
core   +3 more sources

A Case Report of a Very Rare Association of Tyrosinemia type I and Pancreatitis Mimicking Neurologic Crisis of Tyrosinemia Type I

Balkan Medical Journal, 2016
Background: Tyrosinemia type I is an autosomal recessively inherited metabolic disease of tyrosine metabolism due to the deficiency of fumarylacetoacetate hydrolase.
Habibe Koç Uçar, Gökhan Tümgör, Deniz Kör, Neslihan Önenli Mungan, Fatih Kardaş   +4 more
doaj   +1 more source

Transcriptomic responses of Phanerochaete chrysosporium to oak acetonic extracts: focus on a new glutathione transferase. [PDF]

, 2014
The first steps of wood degradation by fungi lead to the release of toxic compounds known as extractives. To better understand how lignolytic fungi cope with the toxicity of these molecules, a transcriptomic analysis of Phanerochaete chrysosporium genes ...
Bchini, Raphael, Bellí i Martínez, Gemma, Chibani, Kamel, Deroy, Aurélie, Dhalleine, Tiphaine, Dumarçay, Stéphane, Gelhaye, Eric, Gérardin, Philippe, Herrero Perpiñán, Enrique, Jacquot, Jean Pierre, Kohler, Annegret, Morel-Rouhier, Mélanie, Thuillier, Anne   +12 more
core   +2 more sources

CRISPR/Cas9‐mediated genome editing: from basic research to translational medicine [PDF]

, 2020
The recent development of the CRISPR/Cas9 system as an efficient and accessible programmable genome-editing tool has revolutionized basic science research. CRISPR/Cas9 system-based technologies have armed researchers with new powerful tools to unveil the
Ferreira, B I, Jacinto, Filipe, Link, Wolfgang   +2 more
core   +1 more source