Results 121 to 130 of about 14,637,911 (412)
Quantitative Measure of Stability in Gene Regulatory Networks [PDF]
arXiv, 2005 A quantitative measure of stability in stochastic dynamics starts to emerge in recent experiments on bioswitches. This quantity, similar to the potential function in mathematics, is deeply rooted in biology, dated back at the beginning of quantitative description of biological processes: the adaptive landscape of Wright (1932) and the development ...
arxiv
Unraveling the Complex Interplay Between T Cell Metabolism and Function.
Annual Review of Immunology, 2018 Metabolism drives function, on both an organismal and a cellular level. In T cell biology, metabolic remodeling is intrinsically linked to cellular development, activation, function, differentiation, and survival.
R. K. Geltink +2 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Cell Death and DiseaseHepatocellular carcinoma (HCC) is one of the most common malignant tumors. Abnormally high expression of Golgi protein 73 (GP73) and pyruvate kinase M2 (PKM2) is intimately associated with HCC progression. However, as secreted proteins, the role of their
Shujie Wang +9 more
doaj +1 more source
Atomic Biology, Electrostatics, and Ionic Channels [PDF]
New Developments and Theoretical Studies of Proteins, Ed. Ron
Elber, World Scientific Publishing, Philadelphia (1996) ISBN-10:9810221967;
ISBN-13:978-9810221966, 2008 I believe an atomic biology is needed to supplement present day molecular biology, if we are to design and understand proteins, as well as define, make, and use them. Topics in the paper are molecular biology and atomic biology. Electrodiffusion in the open channel. Electrodiffusion in mixed electrolytes. Models of permeation.
arxiv
The biology, function, and applications of exosomes in cancer
Acta Pharmaceutica Sinica B, 2021 Jin-yi Liu +9 more
semanticscholar +1 more source
A two-dimensional interpolation function for irregularly-spaced data
ACM National Conference, 1968 In many fields using empirical areal data there arises a need for interpolating from irregularly-spaced data to produce a continuous surface. These irregularly-spaced locations, hence referred to as “data points,” may have diverse meanings: in meterology,
D. Shepard
semanticscholar +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Chemical genetics and strigolactone perception [version 1; referees: 2 approved]
F1000Research, 2017 Strigolactones (SLs) are a collection of related small molecules that act as hormones in plant growth and development. Intriguingly, SLs also act as ecological communicators between plants and mycorrhizal fungi and between host plants and a collection of
Shelley Lumba +2 more
doaj +1 more source
Analysis of Boolean Functions based on Interaction Graphs and their influence in System Biology [PDF]
arXiv, 2014 Interaction graphs provide an important qualitative modeling approach for System Biology. This paper presents a novel approach for construction of interaction graph with the help of Boolean function decomposition. Each decomposition part (Consisting of 2-bits) of the Boolean functions has some important significance.
arxiv