Results 131 to 140 of about 3,596,843 (342)

Molecular Biology and the Functional Psychoses [PDF]

Australian & New Zealand Journal of Psychiatry, 1987
P, Mitchell, B, Waters
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Regulation of ciliary homeostasis by intraflagellar transport-independent kinesins

Cell Death and Disease
Cilia are highly conserved eukaryotic organelles that protrude from the cell surface and are involved in sensory perception, motility, and signaling.
Lin Li, Jie Ran
doaj   +1 more source

Host serine protease ACOT2 assists DENV proliferation by hydrolyzing viral polyproteins

mSystems
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus (DENV). The replication of DENV relies on the processing of its genome-encoded polyprotein by both viral protease NS3 (NS3pro) and host proteases.
Sen Ma, Sai Shi, Binghong Xu, Meijun Liu, Lei Xie, Yang Su, Jiachen Li, Qinqin Liang, Sheng Ye, Yaxin Wang   +9 more
doaj   +1 more source

The long journey to a Systems Biology of neuronal function [PDF]

, 2007
Nicolas Le Novère
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

2SAP-06 Prospect of minority biology(Scenario of functions from minority and number fluctuations,Symposium,The 52th Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Takeharu Nagai
openalex   +2 more sources

Tc17 biology and function: Novel concepts [PDF]

, 2020
Christina Lückel, Felix S.R. Picard, Magdalena Huber   +2 more
openalex   +1 more source