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An overview of microRNAs: Biology, functions, therapeutics, and analysis methods
Journal of Cellular Physiology, 2018MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in posttranscriptional regulation of gene expression. They are powerful regulators of various cellular activities including cell growth, differentiation, development, and apoptosis ...
K. Saliminejad+3 more
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Functional Explanation in Biology
Philosophy of Science, 1965This paper is concerned with the problem of giving a correct analysis of function statements as they are used in biology. Examples of such statements are (1) The function of the myelin sheath is to insulate the nerve fiber and (2) The function of chlorophyll is to enable photosynthesis to take place.
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Ubiquitin Ligases: Structure, Function, and Regulation.
Annual Review of Biochemistry, 2017Ubiquitin E3 ligases control every aspect of eukaryotic biology by promoting protein ubiquitination and degradation. At the end of a three-enzyme cascade, ubiquitin ligases mediate the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to ...
N. Zheng, N. Shabek
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Biology of female sexual function
Urologic Clinics of North America, 2002Although the psychosocial and relationship aspects of female sexuality have been extensively investigated, studies concerning the anatomy, physiology and pathophysiology of female sexual function and dysfunction are limited. The paucity of biologic data may be attributed to a lack of reliable experimental models and tools for investigating female ...
Irwin Goldstein+3 more
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The cell biology of osteoclast function
Journal of Cell Science, 2000ABSTRACT Osteoclasts are multinucleated cells responsible for bone resorption. They have developed an efficient machinery for dissolving crystalline hydroxyapatite and degrading organic bone matrix rich in collagen fibers. When initiating bone resorption, osteoclasts become polarized, and three distinct membrane domains appear: a ruffled
J.M. Halleen+3 more
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A Functional Biology of Nematodes
Journal of the Royal Society of New Zealand, 1986Abstract A Functional Biology of Nematodes is the fifth in a functional biology series which aims to explain how organisms “make a living” in nature, and acquire and make use of resources in metabolism, movement growth, reproduction etc. This book is directed specifically at the research worker and final year undergraduate.
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Leptin: Structure, Function and Biology
2005Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis. Leptin deficiency or resistance can result in profound obesity, diabetes, and infertility in humans. Since its discovery, our understanding of leptin's biological functions has expanded from anti-obesity to broad effects on reproduction ...
Faming Zhang+3 more
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Functional Surfaces in Biology
2009Introduction: Surface Properties and their Functions in Biological Systems.- Protection and Defence.- Biological Properties of Fruit and Seed Slime Envelope: How to Live, Fly, and Not Die.- Easily Damaged Integument of Some Sawflies (Hymenoptera) is Part of a Defence Strategy Against Predators.- Anti-wetting.- Water Repellence in Gecko Skin: How Do ...
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Purpose and Function in Biology
1991There is a sense in which biology is a science much narrower in scope than physics. After all, it deals with, so far as we know, systems that make up only a very small part of the universe.1 On the other hand, it is also true that there is an immense diversity in the sorts of organic systems with which it deals.
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