Results 131 to 140 of about 6,362,947 (287)

Development Blocks, Faulty Investment and Structural Tensions – The Åkerman- Dahmén Theory of the Business Cycle [PDF]

Johan Åkerman and Erik Dahmén’s structural theory of economic fluctuations is a constructive alternative to traditional macroeconomic approaches and also to modern business-cycle models based on micro economic concepts.
Erixon, Lennart
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Are the New Trading Blocs Building or Stumbling Blocks ? A Gravity Model Using Panel Data [PDF]

We will be asking ourselves if the trading blocs created or renewed since the end of the 1980s favor the multilateralization of trade, and so constitute building or stumbling blocks.
Jérôme Trotignon
core  

cric96/ScaFi-Blocks-Web: ScaFi Blocks Web -- Release for COORDINATION 2024 (submitted fix docker)

<p>This is the release related to the artefact submission for COORDINATION 2024.</p> <p>Access the corresponding Docker image here: https://hub.docker.com/repository/docker/gianlucaaguzzi/scafi-blocks/</p ...
Mirko Viroli, Roberto Casadei, Gianluca Aguzzi, Niccolò Maltoni, AleGnucci, casadei-unibo, Manuel Peruzzi   +6 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

FAM20B Gain-of-Function Blocks the Synthesis of Glycosaminoglycan Chains of Proteoglycans and Inhibits Proliferation and Migration of Glioblastoma Cells. [PDF]

Cells
Barré L, Shaukat I, Ouzzine M.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Direct realization of the transfer function using modern fuctional blocks

, 2009
The aim of my bachelor’s thesis is a direct realization of the transfer function using modern functional blocks. It is a circuit design of multifunction frequency-selection filters.
Vyskočil, Jiří
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

cric96/ScaFi-Blocks-Web: ScaFi Blocks Web -- Release for COORDINATION 2024 (submitted)

<p>This is the release related to the artefact submission for COORDINATION 2024.</p> <p>Access the corresponding Docker image here: https://hub.docker.com/repository/docker/gianlucaaguzzi/scafi-blocks/</p ...
Mirko Viroli, Roberto Casadei, Gianluca Aguzzi, Niccolò Maltoni, AleGnucci, casadei-unibo, Manuel Peruzzi   +6 more
core   +1 more source