Results 111 to 120 of about 6,642,147 (292)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Multi-Focus Image Fusion Using Energy Valley Optimization Algorithm
When a natural scene is photographed using imaging sensors commonly used today, part of the image is obtained sharply while the other part is obtained blurry. This problem is called limited depth of field. This problem can be solved by fusing the sharper
Harun Akbulut
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Automated model transformation between MATLAB Simulink/Stateflow and IEC 61499 Function Blocks
This paper presents a new method of modelling automation systems based on the combination and mutual transformation of Function Blocks of IEC 61499 and MATLAB Simulink/Stateflow.
Vyatkin, Valeriy, Yang, ChiaHan,
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Do fascial plane blocks improve respiratory function after breast surgery? [PDF]
Ji Seon Jeong
doaj +1 more source
Targeting PRPK Function Blocks Colon Cancer Metastasis. [PDF]
Zykova T +16 more
europepmc +1 more source
Conformal blocks and Painlevé functions
submitted to RIMS Kokyuroku Bessatsu on January 22 ...
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

