Results 91 to 100 of about 488,957 (273)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Advanced Stability Analysis of Regularized Newton Methods for Monotone Inclusions With Bounded Variation

Journal of Applied Mathematics
This paper presents a comprehensive stability analysis of regularized Newton methods for solving monotone inclusion problems of the form 0∈Ax+Fx, where A is a maximal monotone operator and F is a Lipschitz continuous operator with bounded variation.
Boushra Abbas
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

One-dimensional adhesion model for large scale structures

Electronic Journal of Differential Equations, 2010
We discuss initial value problems and initial boundary value problems for some systems of partial differential equations appearing in the modelling for the large scale structure formation in the universe.
Kayyunnapara Thomas Joseph
doaj  

New approaches to corrected Euler–Maclaurin-type inequalities involving Riemann–Liouville fractional integrals for different function classes

Boundary Value Problems
This paper investigates several Corrected Euler–Maclaurin-type inequalities for different function classes using Riemann–Liouville fractional integrals.
Hasan Kara, Fatih Hezenci, Arslan Munir, Hüseyin Budak   +3 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

A linear functional differential equation with distributions in the input

Electronic Journal of Differential Equations, 2003
This paper studies the functional differential equation $$ dot x(t) = int_a^t {d_s R(t,s), x(s)} + F'(t), quad t in [a,b], $$ where $F'$ is a generalized derivative, and $R(t,cdot)$ and $F$ are functions of bounded variation. A solution is defined by the
Vadim Z. Tsalyuk
doaj  

Grüss–Ostrowski inequalities and bounded variation

Journal of Inequalities and Applications
In this note, we establish corresponding Grüss–Ostrowski-type inequalities for functions with bounded variation. As an application, we provide some estimates for the error in numerical integration rules and estimation for the cumulative distribution ...
Karol Gryszka
doaj   +1 more source