Results 121 to 130 of about 33,941,795 (386)

A Fold Bifurcation Theorem of Degenerate Solutions in a Perturbed Nonlinear Equation

Abstract and Applied Analysis, 2011
We consider a nonlinear equation F(ε,λ,u)=0, where the parameter ε is a perturbation parameter, F is a differentiable mapping from R×R×X to Y, and X, Y are Banach spaces.
Ping Liu, Yuwen Wang
doaj   +1 more source

Principal Component Analysis for Functional Data on Riemannian Manifolds and Spheres

, 2017
Functional data analysis on nonlinear manifolds has drawn recent interest. Sphere-valued functional data, which are encountered for example as movement trajectories on the surface of the earth, are an important special case.
Dai, Xiongtao, Müller, Hans-Georg
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Thrombomodulin is a stronger indicator of combined oral contraceptives-induced activated protein C pathway resistance in the thrombin generation test than activated protein C

Frontiers in Cardiovascular Medicine
BackgroundThe mechanism by which combined oral contraceptives (COCs) lead to hypercoagulation is not fully understood, although activated protein C (APC) pathway resistance has been implicated.
Marisa Ninivaggi, Lily Sokolova, Lily Sokolova, Demy Donkervoort, Bas de Laat, Bas de Laat, Romy de Laat-Kremers   +6 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Transcription factor TFE3 enhances cell cycle and cancer progression by binding to the hTERT promoter

Cancer Communications, 2021
Beiping Miao, Chaoyang Zhang, Nadine Stroh, Lukas Brenner, Katrin Hufnagel, Jörg D. Hoheisel, Obul Reddy Bandapalli   +6 more
doaj   +1 more source

SOME EMBEDDINGS RELATED TO HOMOGENEOUS TRIEBEL–LIZORKIN SPACES AND THE BMO FUNCTIONS

Проблемы анализа
As the homogeneous Triebel–Lizorkin space $\dot{F}_{p,q}^s$ and the space BMO are defined modulo polynomials and constants, respectively, we prove that BMO coincides with the realized space of $\dot{F}_{\infty, 2}^0$ and cannot be directly identified ...
B. Gheribi, M. Moussai
doaj   +1 more source

New Azaphilones from Nigrospora oryzae Co-Cultured with Beauveria bassiana

Molecules, 2018
In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana, the endophytes in the seeds of Dendrobium officinale, were examined for metabolite diversity.
Zhuo-Xi Zhang, Xue-Qiong Yang, Qing-Yan Zhou, Bang-Yan Wang, Ming Hu, Ya-Bin Yang, Hao Zhou, Zhong-Tao Ding   +7 more
doaj   +1 more source