Results 141 to 150 of about 7,524,603 (346)
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Weak Symplectic Functional Analysis and General Spectral Flow Formula
, 2004 We consider a continuous curve of self-adjoint Fredholm extensions of a curve of closed symmetric operators with fixed minimal domain $D_m$ and fixed {\it intermediate} domain $D_W$.
Booss-Bavnbek, Bernhelm, Zhu, Chaofeng
core +1 more source
Introduction to functional analysis for scientists and technologists, by B.Z. Vulikh. Addison-Wesley and Pergamon Press (1963), Reading, Mass. $10.00. [PDF]
, 1965 B. Brainerd
openalex +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Sign-changing solutions for coupled Schrödinger system
Boundary Value ProblemsIn this paper we study the following nonlinear Schrödinger system: { − Δ u + α u = | u | p − 1 u + 2 q + 1 λ | u | p − 3 2 u | v | q + 1 2 , x ∈ R 3 , − Δ v + β v = | v | q − 1 v + 2 p + 1 λ | u | p + 1 2 | v | q − 3 2 v , x ∈ R 3 , u ( x ) → 0 , v ( x )
Jing Zhang
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
A functional analysis of the myelinated fibres of the superior laryngeal nerve of the rat
, 1956 B. L. Andrew
openalex +2 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source