Results 141 to 150 of about 28,831,743 (381)
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Divergent integrals as viewed from the theory of functional analysis, I [PDF]
, 1957 Tadashige Ishihara
openalex +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
On compactness in functional analysis [PDF]
Transactions of the American Mathematical Society, 1955 The theorem of Arzel& and Ascoli, characterizing conditionally compact subsets of the Banach space C(X) of continuous functions defined on a compact topological space X, is fundamental for much of functional analysis. Of less importance but still of interest is the question of characterizing subsets of C(X) which are conditionally compact in other ...
openaire +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Eight Papers on Functional Analysis and Partial Differential Equations [PDF]
, 1957 V. M. Borok +9 more
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More on Jensen functional and convexity [PDF]
arXivIn this paper we prove results on the difference between a normalized Jensen functional and the sum of other normalized Jensen functionals for convex function.
arxiv
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
On Jensen Functional, Convexity and Uniform Convexity [PDF]
arXivIn this paper we improve results related to Normalized Jensen Functional for convex functions and Uniformly Convex Functions.
arxiv
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source