Results 141 to 150 of about 3,444,674 (308)

Functional genomic analysis of K+ related salt-responsive transporters in tolerant and sensitive genotypes of rice

, 2023
Umme Sabrina Haque, Sabrina M. Elias, Israt Jahan, Zeba I. Seraj   +3 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Comparative functional analysis of papaya leaves at different developmental stages. [PDF]

Plant Biotechnol (Tokyo)
Kera K, Soma K, Sugimoto N, Inoue H, Endo A, Iijima M, Suzuki H.   +6 more
europepmc   +1 more source

Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response [PDF]

, 2017
Juthakorn Poothong, Witoon Tirasophon, Randal J. Kaufman   +2 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Functional analysis and verification of GYG2 in oncolytic virus-infected glioma. [PDF]

BMC Cancer
Dong Y, Wang S, Wang C, Zhou J, Zhang Y, Yin X.   +5 more
europepmc   +1 more source

Functional characterization and genomic analysis of stem cell organoids derived from adult mouse gallbladder and intestine tissues

, 2015
Natalia Lugli
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

RE-Aging: A functional analysis platform for human RNA editing associated with aging. [PDF]

Mol Cells
Pan X, Zhang H, Huang W, Ma W, Songyang Z, Xiong Y.   +5 more
europepmc   +1 more source