Results 171 to 180 of about 33,941,795 (386)

Functional Data Analysis

, 2016
Jane-ling Wang, Jeng-Min Chiou, H. Müller   +2 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Multi-tissue Analysis of Co-expression Networks by Higher-Order Generalized Singular Value Decomposition Identifies Functionally Coherent Transcriptional Modules

, 2014
Xiaolin Xiao, Aida Moreno‐Moral, Maxime Rotival, Leonardo Bottolo, Enrico Petretto   +4 more
openalex   +2 more sources

Single‐cell functional analysis of parathyroid adenomas reveals distinct classes of calcium sensing behaviour in primary hyperparathyroidism [PDF]

, 2015
James Koh, Joyce A. Hogue, Yuli Wang, Matthew DiSalvo, Nancy L. Allbritton, Yuhong Shi, John A. Olson, Julie Ann Sosa   +7 more
openalex   +1 more source

Explorative Meta-Analysis of 417 Extant Archaeal Genomes to Predict Their Contribution to the Total Microbiome Functionality [PDF]

, 2021
Robert Starke, Maysa Lima Parente Fernandes, Daniel Morais, Iñaki Odriozola, Petr Baldrián, Nico Jehmlich   +5 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

An energy method for buckling behavior analysis of functionally graded carbon nanotube-reinforced composite sandwich structures [PDF]

, 2022
Shaoqing Wang, Yanmei Qiao, Changcun Liu, Li Luo   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The Hsp90 co-chaperone p23 of Toxoplasma gondii: Identification, functional analysis and dynamic interactome determination

, 2010
Pablo C. Echeverría, María J. Figueras, Malvina Vogler, Thomas Kriehuber, Natalia de Miguel, Bin Deng, Carolina Dalmasso, Dwight E. Matthews, Mariana Matrajt, Martin Haslbeck, Johannes Büchner, Sergio O. Ángel   +11 more
openalex   +2 more sources

Functional analysis of Paracoccidioides brasiliensis 14-3-3 adhesin expressed in Saccharomyces cerevisiae [PDF]

, 2015
Patrícia Akemi Assato, Julhiany de Fátima da Silva, Haroldo César de Oliveira, Caroline Maria Marcos, Danuza Rossi, Sandro Roberto Valentini, Maria José Soares Mendes‐Giannini, Cleslei Fernando Zanelli, Ana Marisa Fusco‐Almeida   +8 more
openalex   +1 more source