Results 301 to 310 of about 33,941,795 (386)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Angiogenesis-related genes and immune microenvironment in moyamoya disease: a transcriptomic and functional analysis. [PDF]

Orphanet J Rare Dis
Zhou Z, Niu H, Xu S, Zhang J, Liu Y, Lei C, He S, Zhao Y.   +7 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Functional analysis of the effect of isoimperatorin on human acute monocytic leukemia at the transcriptome level. [PDF]

Oncol Lett
Yin R, Xu R, Ming H, Song J.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Isolation of live human δ cells for genetic and functional analysis. [PDF]

Mol Metab
Hang Y, Miranda MA, Yan Z, Zhao W, Kim SK.   +4 more
europepmc   +1 more source

Circular RNA profiling and functional analysis implicate circ-ANKRD36C as a potential prognostic biomarker in gastric cancer. [PDF]

BMC Gastroenterol
Chen R, Ji T, Chu Y, Xiao F, Feng Z, Wang G.   +5 more
europepmc   +1 more source

Identification and functional analysis of Wall-Associated Kinase genes in Nicotiana tabacum

Ling Li, Linggai Cao, Jintao Li, Zhiqiang Zhang, Jie Liu, Zhongying Ren, Jie Zhang, Rengang Wang, Yuanyuan Miao, Shizhou Yu, Wei Li   +10 more
openalex   +1 more source

Identification and functional analysis of two oligopeptide transporters supporting the growth of <i>Lacticaseibacillus paracasei</i> strain Shirota in milk. [PDF]

Microbiology (Reading)
Tanaka S, Serata M, Terai T, Fujii D, Okumura T.   +4 more
europepmc   +1 more source