Results 61 to 70 of about 4,216,104 (317)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An integrated experimental and analytical approach for the analysis of the mechanical interaction between metal porous scaffolds and bone: implications for stress shielding in orthopedic implants

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionMetal porous structures are becoming a standard design feature of orthopedic implants such as joint endoprostheses. The benefits of the pores are twofold: 1) help improve the cementless primary stabilization of the implant by increasing ...
Roberto Ramaglia Amadasi   +4 more
doaj   +1 more source

Analysis of Brownian functionals [PDF]

open access: yes, 1976
We discuss functionals of Brownian motion by expressing them as those of white noise. We then proceed to generalize them to obtain generalized functionals of Brownian motion. Throughout this paper the integral representation of those functionals is a powerful tool.
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A reversal coarse-grained analysis with application to an altered functional circuit in depression [PDF]

open access: yes, 2013
Introduction: When studying brain function using functional magnetic resonance imaging (fMRI) data containing tens of thousands of voxels, a coarse-grained approach – dividing the whole brain into regions of interest – is applied frequently to ...
Shuixia Guo   +7 more
core   +1 more source

GC and GC/MS analyses of the Algerian Lantana camara leaf essential oil: Effect against Sitophilus granarius adults

open access: yesJournal of Saudi Chemical Society, 2011
The bioactivity of the essential oil extracted by hydrodistillation from Lantana camara leaves was assessed under laboratory conditions. The composition of L.
Safia Zoubiri, Aoumeur Baaliouamer
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Robust, Adaptive Functional Regression in Functional Mixed Model Framework [PDF]

open access: yes, 2011
Functional data are increasingly encountered in scientific studies, and their high dimensionality and complexity lead to many analytical challenges.
Morris, Jeffrey S.   +5 more
core   +1 more source

Warped functional analysis of variance [PDF]

open access: yesBiometrics, 2014
SummaryThis article presents an Analysis of Variance model for functional data that explicitly incorporates phase variability through a time‐warping component, allowing for a unified approach to estimation and inference in presence of amplitude and time variability.
Gervini, Daniel, Carter, Patrick A.
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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