Results 121 to 130 of about 1,525,960 (267)

Salivary Dysfunction in Primary and Secondary Sjögren's Syndrome: Functional Assessment and the Exploratory Role of Salivary Microcrystallization. [PDF]

Dent J (Basel)
Ghiorghe CA, Tărăboanţă I, Iordache C, Ancuţa C, Lodbă A, Topoliceanu C, Sălceanu M, Iovan G, Nica I, Pancu G.   +9 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Multilevel Genetic and Functional Assessment of an ARR3 Frameshift Variant in Early-Onset High Myopia. [PDF]

Int J Genomics
Li Y, Teng F, Zhu Q, Cui S, Yang W, Ma P.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Functional assessment of a constitutively activating <i>CASR</i> variant causing autosomal dominant hypocalcemia. [PDF]

J Endocr Soc
Ward BK, Stuckey BGA, Walsh JP, Conigrave AD, Brown SJ, Wilson SG.   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Reliability and Validity Study of the International Classification of Functioning，Disability and Health Rehabilitation Set in Rehabilitation of Knee Osteoarthritis

康复学报
ObjectiveTo explore the reliability and validity of the International Classification of Functioning, Disability and Health Rehabilitation Set (ICF-RS) in assessing the body function, activities and social participation of patients with knee ...
LEI Lei, PENG Zhizhou, GAO Mingyue, LI Fei, MAO Ningning, WU Xi, XIAO Chengcheng, XUN Yajing, ZHAO Suchen, FAN Xiaojun   +9 more
doaj  

Multimodal Functional Assessment of Asymmetries in Youth Soccer Players: Study Protocol. [PDF]

Life (Basel)
Codreanu AM, Korodi DA, Lupu NA, Onciulenco AV, Vataman AA, Duse AO, Rezumes MZ, Amaricai EC, Catan L, Caraba A, Onofrei RR, Borza C.   +11 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The Functional Impingement Subacromial Ultrasound (FISUN) test: a conceptual and methodological framework for functional assessment of the subacromial space. [PDF]

Ultrasonography
Niewiadomy P, Szuścik-Niewiadomy K.
europepmc   +1 more source