Results 61 to 70 of about 1,525,960 (267)

Relationships between selected elements of physical and functional fitness and the competitive performance of judo athletes

Revista de Artes Marciales Asiáticas
Judo competitors at the highest sports skill level are characterized by a high level of physical fitness, mental toughness, and technical skills developed through years of training.
Dariusz Boguszewski
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Case Report: Fabrication of a plumper-type music splint for saxophone performance in a patient with a full-arch implant-supported prosthesis

Frontiers in Dental Medicine
IntroductionThe orofacial region, particularly the lips, tongue, and teeth, plays a critical role in wind instrument performance. Wind instrument players may experience lip pain, trauma, or discomfort during performance.
Mariko Hattori, Yuichi Yamatani, Yuka Sumita, Yuka Sumita, Noriyuki Wakabayashi   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Editorial: Tools and strategies that promote the return to work and stay at work of people with disabilities—contributions from occupational therapy and other disciplines centered on the biopsychosocial approach

Frontiers in Rehabilitation Sciences, 2023
Edda Capodaglio, Enrico Oddone
doaj   +1 more source

Tactile sensation moderates the association between hand dexterity and higher-level cognition in older adults with and without MCI

Frontiers in Aging Neuroscience
BackgroundTactile sensation and hand dexterity decline with age and are associated with later-life cognition, yet it remains unclear whether tactile sensation moderates the strength of hand motor–cognitive associations.
Kimi Estela Kobayashi-Cuya, Ryota Sakurai, Susumu Ogawa, Hiroko Matsunaga, Keigo Hinakura, Shun Yoshikoshi, Shun Yoshikoshi, Yan Li, Maki Nishinakagawa, Hiroyuki Suzuki   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Electromyographic Activity of the Upper Limb in Three Hand Function Tests

Hong Kong Journal of Occupational Therapy, 2017
Objective/Background: Occupational therapists usually assess hand function through standardised tests, however, there is no consensus on how the scores assigned to hand dexterity can accurately measure hand function required for daily activities and few ...
Natália Sanches Silva, Pedro Henrique Tavares Queiroz de Almeida, Paulo Vinícius Braga Mendes, Caio Sadao Medeiros Komino, José Marques Novo Jùnior, Daniel Marinho Cezar Da Cruz   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Physical resilience and healthy aging

Shiyong laonian yixue
Global population aging underscores the urgent need to advance healthy aging as a public health priority.Physical resilience, as the core capacity of older adults to maintain or restore functional stability when exposed to physiological stressors such as
WANG Jiao, DENG Yiping, ZHANG Liying, GE Ning, YUE Jirong, GAO Langli   +5 more
doaj   +1 more source