Results 71 to 80 of about 1,525,960 (267)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Background: Patellar tendon complaints and other tendon-related disorders are common in jumping sports; however, the relationship between recorded tendon problems, anthropometric characteristics, and neuromuscular performance in youth athletes remains ...
Gaetano Raiola +5 more
doaj +1 more source
The Functional Assessment Inventory [PDF]
Andy, Tyerman, Ruth, Tyerman
openaire +2 more sources
Pancreatic function assessment.
Several non invasive tests are available to assess pancreatic function, but no one is routinely used in clinical practice to diagnose chronic pancreatitis, due to their poor sensitivity in diagnosing mild pancreatic insufficiency. (13)C breath tests share the same limits of the other non invasive functional tests, but the mixed triglyceride breath test
Laterza L +9 more
openaire +3 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
BackgroundComprehensive assessment of functioning in fibromyalgia (FM) requires the integration of objective and subjective outcome measures. Although performance-based tests (PBTs) are increasingly recommended for evaluating physical function, evidence ...
José Luis Socorro-Cumplido +15 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
A two-factor feeding trial evaluated the effects of soybean oil (SO) and cottonseed oil (CO), at 50 % or 100 % dietary lipid inclusion on growth, lipid metabolism, and fillet quality in largemouth bass (Micropterus salmoides). A total of 120 fish (51.66 ±
Yangyang Liu +6 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Background and Objectives: This study aimed to investigate the magnitude of vertical jump inter-limb asymmetries among young highly-trained basketball athletes and to analyze its impact on sport performance, specifically in sprints, agility, and vertical
Fernando Domínguez-Navarro +3 more
doaj +1 more source

