Results 121 to 130 of about 4,689,287 (347)
Most quantum logics do not allow for a reasonable calculus of conditional probability. However, those ones which do so provide a very general and rich mathematical structure, including classical probabilities, quantum mechanics, and Jordan algebras. This
Gerd Niestegge
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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A Direct Approach to Shape Optimisation of Structures
Shape optimisation of structures constitutes - mathematically a non-standard problem of the calculus of variations consisting in searching for the conditional extremum of a functional which does not possess, as a rule, a "localization property".
Z.K. Leśniak
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A Fluent Calculus Approach to Automatic Web Service Composition
Web service composition is mandatory when complex functional requirements cannot be satisfied by a single Web service. Because of the exponential growth of available Web services, their automatic discovery and composition are highly desirable tasks. This
CHIFU, V., SALOMIE, I.
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An Application of the $S$-Functional Calculus to Fractional Diffusion\n Processes [PDF]
Fabrizio Colombo, Jonathan Gantner
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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
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The Lazy Lambda Calculus: an investigation into the foundations of functional programming
C.-H. Luke Ong
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
This paper develops integral inequalities for first-order differentiable convex functions within the framework of fractional calculus, extending Boole-type inequalities to this domain. An integral equality involving Riemann–Liouville fractional integrals
Abdul Mateen +4 more
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