Results 71 to 80 of about 137,290 (281)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Topography and behavioral relevance of the global signal in the human brain
Scientific Reports, 2019 The global signal in resting-state functional MRI data is considered to be dominated by physiological noise and artifacts, yet a growing literature suggests that it also carries information about widespread neural activity.
Jingwei Li +6 more
doaj +1 more source
Bioinformatics and moonlighting proteins
Frontiers in Bioengineering and Biotechnology, 2015 Multitasking or moonlighting is the capability of some proteins to execute two or more biochemical functions. Usually, moonlighting proteins are experimentally revealed by serendipity.
Sergio eHernández +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Multi-set canonical correlation analysis in action-observation (mirror neuron) study
, 2020 Optics and the Brain 2020, Washington, DC United States 20–23 April 2020We used simultaneous functional near infrared spectroscopy along with electroencephalography to investigate mirror neuron network in human brain.
Millerhagen, John +4 more
core +1 more source
Robust estimation in canonical correlation analysis for multivariate functional data
Hacettepe Journal of Mathematics and Statistics, 2018 Summary: In this paper, the canonical correlation analysis for multivariate functional data is considered. The analysis is based on the basis functions representation of the data. The use of non-orthogonal bases is available in contrast to the approach given in the literature.
KRZYŚKO, Mirosław, SMAGA, łukasz
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The general theory of canonical correlation and its relation to functional analysis [PDF]
Journal of the Australian Mathematical Society, 1961 The classical theory of canonical correlation is concerned with a standard description of the relationship between any linear combination of ρ random variablesxs, and any linear combination ofqrandom variablesytinsofar as this relation can be described in terms of correlation.
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Adolescent brain maturation associated with environmental factors: a multivariate analysis
Frontiers in NeuroimagingHuman adolescence marks a crucial phase of extensive brain development, highly susceptible to environmental influences. Employing brain age estimation to assess individual brain aging, we categorized individuals (N = 7,435, aged 9–10 years old) from the ...
Bhaskar Ray +17 more
doaj +1 more source