Results 91 to 100 of about 838,497 (309)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Functional Random Forest for Biomedical Signals Classification and Interpretative Tools
, 2022 This study deals with tree-based techniques and functional data analysis (FDA) [1] for supervised classification of curves representing high-dimensional biomedical data recorded over time.
Fabrizio, Maturo, Rosanna, Verde
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Long-Term Outcome after Pneumonectomy at Siriraj Hospital
Siriraj Medical Journal, 2020 Objective: The purpose of this study is to identify predictors of long term survival following pneumonectomy and compare New York Heart Association (NYHA) functional classification and ECOG performance status before and after surgery at Siriraj Hospital.
Wanchai Wongkornrat +8 more
doaj
DEPTH-BASED CLASSIFICATION FOR FUNCTIONAL DATA [PDF]
Classification is an important task when data are curves. Recently, the notion of statistical depth has been extended to deal with functional observations.
Juan Romo, Sara Lopez-Pintado
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A functional classification of metropolitan communities [PDF]
Demography, 1973 Abstract Five major approaches to the functional classification of communities have been offered. Although most of them allow the recognition of a community as specialized in more than one function, their application necessitates consideration of the several individual functions one at a time.
openaire +2 more sources
Functional assessment of urban forested wetlands. [PDF]
, 2006 Wetlands perform various functions of vital socio-ecological significance. To avoid further loss of functions, functional assessment techniques for management purposes are important to develop for different wetland classes.
Faulkner, Stepehn, Ullah, Sami
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Wavelet-RKHS-based functional statistical classification
, 2012 A functional classification methodology, based on the Reproducing Kernel Hilbert Space (RKHS) theory, is proposed for discrimination of gene expression profiles.
Rincón Hidalgo, Margarita María; Ruiz Medina, María Dolores
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