Results 61 to 70 of about 704,566 (347)

Quasi-periodic patterns of brain activity in individuals with attention-deficit/hyperactivity disorder

NeuroImage: Clinical, 2019
Individuals with attention-deficit/hyperactivity disorder have disrupted functional connectivity in the default mode and task positive networks. Traditional fMRI analysis techniques that focus on ‘static’ changes in functional connectivity have been ...
Anzar Abbas, Yasmine Bassil, Shella Keilholz   +2 more
doaj   +1 more source

Evaluating methods for measuring background connectivity in slow event‐related functional magnetic resonance imaging designs

Brain and Behavior, 2023
Introduction Resting‐state functional magnetic resonance imaging (fMRI) is widely used for measuring functional interactions between brain regions, significantly contributing to our understanding of large‐scale brain networks and brain–behavior ...
Lea E. Frank, Dagmar Zeithamova
doaj   +1 more source

Abnormal connectivity between the default mode and the visual system underlies the manifestation of visual hallucinations in Parkinson’s disease:A task-based fMRI study [PDF]

, 2015
Background: The neural substrates of visual hallucinations remain an enigma, due primarily to the difficulties associated with directly interrogating the brain during hallucinatory episodes.
Halliday, Glenda M., Hornberger, Michael, Lewis, Simon J. G., Muller, Alana J., O’Callaghan, Claire, Shine, James M.   +5 more
core   +1 more source

Bacterial protein interaction networks: connectivity is ruled by gene conservation, essentiality and function [PDF]

, 2020
Protein-protein interaction (PPI) networks are the backbone of all processes in living cells. In this work we relate conservation, essentiality and functional repertoire of a gene to the connectivity $k$ of the corresponding protein in the PPI networks ...
Cimini, Giulio, Dilucca, Maddalena, Giansanti, Andrea   +2 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Simple individual-based models effectively represent Afrotropical forest bird movement in complex landscapes [PDF]

, 2014
Reliable estimates of dispersal rates between habitat patches (i.e. functional connectivity) are critical for predicting long-term effects of habitat fragmentation on population persistence.
Aben, Job, Adriaensen, Frank, Lens, Luc, Matthysen, Erik, Palmer, Stephen CF, Strubbe, Diederik, Travis, Justin MJ   +6 more
core   +1 more source

Inferring functional connections between neurons [PDF]

Current Opinion in Neurobiology, 2008
A central question in neuroscience is how interactions between neurons give rise to behavior. In many electrophysiological experiments, the activity of a set of neurons is recorded while sensory stimuli or movement tasks are varied. Tools that aim to reveal underlying interactions between neurons from such data can be extremely useful.
Ian H, Stevenson, James M, Rebesco, Lee E, Miller, Konrad P, Körding   +3 more
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Altered resting-state functional connectivity of the frontal-striatal reward system in social anxiety disorder.

PLoS ONE, 2015
We investigated differences in the intrinsic functional brain organization (functional connectivity) of the human reward system between healthy control participants and patients with social anxiety disorder.
Joshua Manning, Gretchen Reynolds, Zeynep M Saygin, Stefan G Hofmann, Mark Pollack, John D E Gabrieli, Susan Whitfield-Gabrieli   +6 more
doaj   +1 more source

Age-Related Decline in the Variation of Dynamic Functional Connectivity: A Resting State Analysis

Frontiers in Aging Neuroscience, 2017
Normal aging is typically characterized by abnormal resting-state functional connectivity (FC), including decreasing connectivity within networks and increasing connectivity between networks, under the assumption that the FC over the scan time was ...
Yuanyuan Chen, Yuanyuan Chen, Weiwei Wang, Weiwei Wang, Xin Zhao, Xin Zhao, Miao Sha, Miao Sha, Ya’nan Liu, Ya’nan Liu, Xiong Zhang, Xiong Zhang, Jianguo Ma, Hongyan Ni, Dong Ming, Dong Ming   +15 more
doaj   +1 more source