Results 41 to 50 of about 110,658 (234)

Potential-Driven Adiabatic Connection in Density Functional Theory [PDF]

open access: yesJournal of Chemical Theory and Computation, 2009
As density functional theory conventionally assumes that the density of a chosen model system (e.g., the Kohn-Sham system) is the same as the exact one, one might expect that approximations to the exact density introduce supplementary errors by falsifying the density.
openaire   +3 more sources

Resting‐state default mode network connectivity in young individuals with Down syndrome

open access: yesBrain and Behavior, 2021
Background Down syndrome (DS) is a chromosomal disorder that causes intellectual disability. Few studies have been conducted on functional connectivity using resting‐state fMRI (functional magnetic resonance imaging) signals or more specifically, on the ...
María Dolores Figueroa‐Jimenez   +6 more
doaj   +1 more source

Reserve design to optimize functional connectivity and animal density

open access: yesConservation Biology, 2019
Abstract Ecological distance‐based spatial capture–recapture models (SCR) are a promising approach for simultaneously estimating animal density and connectivity, both of which affect spatial population processes and ultimately species persistence.
Amrita Gupta   +6 more
openaire   +3 more sources

A Comparative Study of the Effect of Weighted or Binary Functional Brain Networks in fMRI Data Analysis

open access: yesFrontiers in Biomedical Technologies, 2020
Purpose: Graph theory is a widely used and reliable tool to quantify brain connectivity. Brain functional connectivity is modeled as graph edges employing correlation coefficients.
Hessam Ahmadi   +2 more
doaj   +1 more source

Detecting Early Cognitive Decline in Alzheimer’s Disease with Brain Synaptic Structural and Functional Evaluation

open access: yesBiomedicines, 2023
Early cognitive decline in patients with Alzheimer’s (AD) is associated with quantifiable structural and functional connectivity changes in the brain. AD dysregulation of Aβ and tau metabolism progressively disrupt normal synaptic function, leading to ...
Samo Ribarič
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Abnormal Functional Brain Network in Parkinson's Disease and the Effect of Acute Deep Brain Stimulation

open access: yesFrontiers in Neurology, 2021
Objective: The objective of this study was to use functional connectivity and graphic indicators to investigate the abnormal brain network topological characteristics caused by Parkinson's disease (PD) and the effect of acute deep brain stimulation (DBS)
Zhibao Li   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Connection formulas for thermal density functional theory

open access: yesPhysical Review B, 2016
The adiabatic connection formula of ground-state density functional theory relates the correlation energy to a coupling-constant integral over a purely potential contribution, and is widely used to understand and improve approximations. The corresponding formula for thermal density functional theory is cast as an integral over temperatures instead ...
Pribram-Jones, Aurora, Burke, Kieron
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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