Results 141 to 150 of about 4,566,680 (308)

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma, Panagiota Tsitsi, Nirosen Vijiaratnam, Camila Aquino, Stephen R. Duma, Norbert Kovacs, Kigocha Lameck Okeng'o, Aparna Wagle Shukla, Roongroj Bhidayasiri, Tiago A. Mestre, Alvaro Sanchez Ferro, Alberto J. Espay, Michelle H.S. Tosin, Matej Skorvanek, Ioanna Markaki   +14 more
wiley   +1 more source

Effects of a Four‐Strain Probiotic on Gut Microbiota, Inflammation, and Symptoms in Parkinson's Disease: A Randomized Clinical Trial

Movement Disorders, EarlyView.
Abstract Background Gut dysbiosis and gut‐brain‐axis involvement in people with Parkinson's disease (PwP) support the use of gut‐microbiota‐modulating interventions. Probiotics may help manage constipation in PwP; however, mechanisms underpinning additional beneficial properties are unknown.
Valentina Leta, Pavlos Zinzalias, Lucia Batzu, Gargi Mandal, Juliet Staunton, Frida Jernstedt, Kristina Rosqvist, Jonathan Timpka, Trinette van Vliet, Dhaval Trivedi, Aleksandra Podlewska, Miriam Parry, Daniel J. van Wamelen, Alexandra Rizos, Carolina Sportelli, Ana Laura Bonder, Guy Chung‐Faye, Cristian Falup‐Pecurariu, Simon Gaisford, Edoardo Moretto, Gwenaelle Le Gall, David Vauzour, Ana Rodriguez‐Mateos, Anna Sauerbier, Carmen Rodriguez Blazquez, Jonas Ghyselinck, Benoît Marsaux, Carmine Maria Pariante, Alessandra Borsini, Per Odin, Kallol Ray Chaudhuri   +30 more
wiley   +1 more source

Sympathetic Shift and Insular Alteration: Unravelling the Link Between Anxiety and Heart Rate Variability in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Anxiety and autonomic dysfunction are frequent non‐motor symptoms of Parkinson's disease (PD). Their relationship, as well as the neural mechanisms underlying this relationship, remain unexplored. Objectives We aimed to investigate the relationship between cardiovascular functions and anxiety in PD and the structural neural changes ...
Lucia Ricciardi, Alessandra Fanciulli, Francescopaolo P. Cucinotta, Bryony Ishihara, Ioana Cociasu, Fahd Baig, Michael Hart, Erlick Pereira, Francesca Morgante, Elena Makovac   +9 more
wiley   +1 more source

Efficacy and Safety of Maxing Xianchang Su in the Treatment of Functional Constipation: A Randomized Controlled Trial [PDF]

, 2021
Mi Li, Lijuan Zhao, Li Ma, Wen Zhang, Hua Huang, Jun Wei, Jun Sun, Fenying Lu, Lijiang Ji   +8 more
openalex   +1 more source

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho, Julia C. Greenland, Alexander R.D. Peattie, Lennart R.B. Spindler, Jonathan Holbrook, Lakmini Kahanawita, Tim D. Fryer, Young T. Hong, Caroline H. Williams‐Gray   +8 more
wiley   +1 more source

Subcutaneous Foslevodopa as Rescue Therapy for Abrupt Interruption of Oral Dopaminergic Treatment in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Fabienne Ory‐Magne, Jean Luc Houeto, Margherita Fabbri   +2 more
wiley   +1 more source

Bifidobacteria and Celiac Disease: Mechanisms of Probiotic Action in Reducing Gluten‐Induced Cytotoxicity and Inflammation

Molecular Nutrition &Food Research, EarlyView.
Celiac disease (CD) is triggered by gluten in genetically predisposed individuals and is mainly treated with a gluten‐free diet. However, symptoms may persist. This review explores how certain Bifidobacterium strains may reduce inflammation and gluten toxicity through six mechanisms, including modulation of immune responses and gut microbiota.
Taynara Cipriano Scherer, Ivan De Marco, Natália Regina Coldebella Ferreira, Tatiana Colombo Pimentel, Marciane Magnani, Guilherme de Souza Hassemer, Amanda Bagolin do Nascimento, Silvani Verruck   +7 more
wiley   +1 more source

Obesity and functional constipation in children

, 2018
Natasha Yuwanita, Atan Baas Sinuhaji, Tiangsa Sembiring, Supriatmo Supriatmo, Ade Rachmat Yudiyanto   +4 more
openalex   +1 more source

Understanding Parents’ Experiences When Caring for a Child With Functional Constipation: Interpretive Description Study [PDF]

, 2020
Alison P Thompson, Shannon E. MacDonald, Eytan Wine, Shannon D. Scott   +3 more
openalex   +1 more source

A Global Transcriptomic Analysis Reveals Body Weight‐Specific Molecular Responses to Chronic Orange Juice Consumption in Healthy Individuals

Molecular Nutrition &Food Research, EarlyView.
This study aimed to investigate the molecular pathways involved in the health benefits of chronic orange juice (OJ) consumption through global transcriptomic approach in peripheral blood mononuclear cells (PBMCs). Healthy volunteers consumed 500 mL of OJ daily for 60 days.
Layanne Nascimento Fraga, Dragan Milenkovic, Isabella de Araújo Esteves Duarte, Saivageethi Nuthikattu, Camille Perella Coutinho, Franco Maria Lajolo, Neuza Mariko Aymoto Hassimotto   +6 more
wiley   +1 more source