Results 81 to 90 of about 4,566,680 (308)

Exploring the mechanism of interaction between Muc2 and intestinal flora on functional constipation [PDF]

, 2023
Kuang Mengfei, Ya Liu, Dan Xu, Jiang Hua
openalex   +1 more source

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Impact of breastfeeding during infancy on functional constipation at 3 years of age: the Japan Environment and Children’s Study

International Breastfeeding Journal, 2023
Background There is a lack of large, nationwide, birth cohort studies in Japan that examine the relationships of initial feeding habits and breastfeeding period duration with offspring functional constipation at 3 years of age.
Noriko Motoki, Yuji Inaba, Hirokazu Toubou, Kohei Hasegawa, Takumi Shibazaki, Teruomi Tsukahara, Tetsuo Nomiyama, the Japan Environment and Children’s Study (JECS) Group   +7 more
doaj   +1 more source

Quantification of Intestinal Lactobacillus Species in Children with Functional Constipation by Quantitative Real-Time PCR

Clinical and Experimental Gastroenterology, 2020
Background Functional constipation is a common and annoying gastrointestinal disorder among children worldwide in which the intestinal microbiota composition plays a fundamental role.
Dr. Nabi Jomehzadeh, H. Javaherizadeh, M. Amin, Mohammad Rashno, A. Teimoori   +4 more
semanticscholar   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

The Diagnostic Accuracy of Abdominal X-ray in Childhood Constipation: A Systematic Review of the Literature

Gastrointestinal Disorders
Background: Previous systematic reviews have found insufficient and conflicting evidence for an association between the clinical and radiographic diagnosis of functional constipation.
David Avelar Rodriguez, Ghaida Dahlwi, Michelle Gould, Margaret Marcon, Marc Benninga   +4 more
doaj   +1 more source

Modulation of Gut Microbiota by Protein‐Oligosaccharide Maillard‐Reaction‐Derived Probiotic Microcapsules

Food Bioengineering, EarlyView.
Development of a novel synbiotic microcapsule and its impact on gut microbiota. ABSTRACT As a new type of prebiotic, the Maillard reaction products of protein ‐ oligosaccharide conjugates have emerged as a promising material for probiotic encapsulation and improve host health.
Hongxing Zhang, Yue Shen, Wanting Huang, Xinyi Fang, Yanlin Wang, Xingyuan Ma, Wenyun Zheng   +6 more
wiley   +1 more source

Pediatric Functional Constipation: A New Challenge

Advanced Gut & Microbiome Research
Functional constipation is a common gastrointestinal disorder worldwide in children, adolescents, and adults. Functional constipation is persistent, difficult, and infrequent hard stooling with incomplete rectal emptying that does not have an ...
Samina Khan Bashir, Muhammad Bashir Khan
doaj   +1 more source

Brain Structural Changes in Regions Within the Salience Network in Patients with Functional Constipation [PDF]

, 2021
Zhenzhen Jia, Guanya Li, Yang Hu, Hao Li, Wenchao Zhang, Jia Wang, Lei Zhang, Zongxin Tan, Shuai Lv, Karen M. von Deneen, Shijun Duan, Guangbin Cui, Yi Zhang, Yongzhan Nie   +13 more
openalex   +1 more source