Results 121 to 130 of about 33,054,453 (365)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Applied Functional Data Classification
, 2018 Picomole is a New Brunswick based company developing a lung cancer diagnosis system based on a person’s breath sample. Picomole conducted two different studies in an effort to ascertain whether their breath analysis system utilizing cavity ringdown ...
Babyn, Jonathan
core
Association Analysis Techniques for Discovering Functional Modules from Microarray Data
, 2008 An application of great interest in microarray data analysis is the identification of a group of genes that show very similar patterns of expression in a data set, and are expected to represent groups of genes that perform common/similar functions, also ...
Gaurav Pandey +3 more
core +1 more source
, 2023 The dataset contains the raw data for the paper published in advanced functional materials titled as: Elucidating the Role of Chalcogenide-Based Interface Passivators in Enhancing the Stability of Perovskite Solar ...
Sadhu, Anupam
core +1 more source
Registration for Exponential Family Functional Data
Biometrics, 2018 We introduce a novel method for separating amplitude and phase variability in exponential family functional data. Our method alternates between two steps: the first uses generalized functional principal components analysis to calculate template functions,
J. Wrobel +3 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Rainbow plots, Bagplots and Boxplots for Functional Data [PDF]
We propose new tools for visualizing large numbers of functional data in the form of smooth curves or surfaces. The proposed tools include functional versions of the bagplot and boxplot, and make use of the first two robust principal component scores ...
Rob J. Hyndman, Han Lin Shang
core
FILTRATED COMMON FUNCTIONAL PRINCIPAL COMPONENT ANALYSIS OF MULTIGROUP FUNCTIONAL DATA
Local field potentials (LFPs) are signals that measure electrical activities in localized cortical regions and are collected from multiple tetrodes implanted across a patch on the surface of cortex.
Jiao, Shuhao +2 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Modelling intra-daily volatility by functional data analysis: an empirical application to the spanish stock market [PDF]
, 2009 We propose recent functional data analysis techniques to study the intra-daily volatility. In particular, the volatility extraction is based on functional principal components and the volatility prediction on functional AR(1) models.
Ruiz Ortega, Esther +8 more
core