Results 91 to 100 of about 65,551 (301)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Treebank-based acquisition of a Chinese lexical-functional grammar [PDF]

open access: yes, 2004
Scaling wide-coverage, constraint-based grammars such as Lexical-Functional Grammars (LFG) (Kaplan and Bresnan, 1982; Bresnan, 2001) or Head-Driven Phrase Structure Grammars (HPSG) (Pollard and Sag, 1994) from fragments to naturally occurring ...
O'Donovan, Ruth   +8 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mining functional dependencies [PDF]

open access: yes, 2001
We implemented a system to mine functional dependencies from relational databases. Our system improved current technology by employing an SQL interface between the database and the mining module.
Ciman, Michael C.   +1 more
core  

On functional dependencies in q-Horn theories [PDF]

open access: yes, 2001
This paper studies functional dependencies in q-Horn theories, and discusses their use in knowledge condensation. We introduce compact model-based representations of q-Horn theories, analyze the structure of functional dependencies in q-Horn theories ...
Toshihide Ibaraki   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Functional dependencies for XML [PDF]

open access: yes, 2007
In relational the concept of functional dependencies is well established and was used in integrity enforcement and in database design. Functional dependencies were used to specify the constraints and discover data redundancies that may exist in the ...
Ibrahim, Hamidah   +3 more
core  

Home - About - Disclaimer - Privacy