FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Cognitive impairment in older people: its implications for future demand for services and costs [PDF]
, 2003 This study aimed to make projections, for the next 30 years, of future numbers of older people with cognitive impairment, their demand for long-term care services and the future costs of their care under a range of specified assumptions.
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
AN ALTERNATIVE CONCEPT OF FUZZY FUNCTIONAL DEPENDENCY BY USING CONDITIONAL PROBABILITY
Jurnal Informatika, 2001 This paper proposes an alternative concept of Fuzzy Functional Dependency (FFD) based on the theory of conditional probability. We examine some properties of conditional probability and its relation with fuzzy sets.
Rolly Intan
doaj
Functional dependency and COVID-19 in elderly patients with mild to moderate disease. Experience of tertiary geriatric hospital. [PDF]
Exp Gerontol, 2022 Emily L, Gilad G, Haim ME, Galina G.
europepmc +1 more source
A Method for Mapping XML DTD to Relational Schemas In The Presence Of Functional Dependencies [PDF]
, 2008 The eXtensible Markup Language (XML) has recently emerged as a standard for data representation and interchange on the web. As a lot of XML data in the web, now the pressure is to manage the data efficiently.
Ahmad, Kamsuriah
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Functional capacity and social support to people affected by cerebrovascular accident
Revista Brasileira de EnfermagemObjective: To investigate the functional capacity and its relationship with the level of social support to people affected by cerebrovascular accident. Methods: Cross-sectional and quantitative research, conducted with 108 individuals with sequelae of ...
Raquel Janyne de Lima +7 more
doaj +1 more source
Neuropsychological Predictors of Severe Functional Dependency in a Multiethnic Community Cohort of Individuals with Alzheimer's Disease. [PDF]
J Alzheimers Dis, 2021 Cárcamo J +6 more
europepmc +1 more source