Results 51 to 60 of about 3,507,101 (291)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
DCU 250 Arabic dependency bank: an LFG gold standard resource for the Arabic Penn treebank [PDF]
, 2006 This paper describes the construction of a dependency bank gold standard for Arabic, DCU 250 Arabic Dependency Bank (DCU 250), based on the Arabic Penn Treebank Corpus (ATB) (Bies and Maamouri, 2003; Maamouri and Bies, 2004) within the theoretical ...
Dichy, J. +3 more
core +3 more sources
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2020 Background Rehabilitation is effective for multiple sclerosis, but is it value for money? Objectives To evaluate functional outcomes, care needs and cost-efficiency of specialist inpatient rehabilitation for adults with multiple sclerosis (MS). Methods A
Lynne Turner-Stokes +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lossless Join Decomposition for Extended Possibility-Based Fuzzy Relational Databases
Journal of Applied Mathematics, 2014 Functional dependency is the basis of database normalization. Various types of fuzzy functional dependencies have been proposed for fuzzy relational database and applied to the process of database normalization. However, the problem of achieving lossless
Julie Yu-Chih Liu
doaj +1 more source
EClinicalMedicine, 2022 Summary: Background: Older people are more likely to be excluded from the digital world, and this has been linked to poor health outcomes. The extent and direction of the influence of digital exclusion on functional dependency is, however, not well ...
Xinran Lu, Yao Yao, Yinzi Jin
doaj +1 more source
, 2021 Optimality of syntactic dependency distances Preprocessed data and code for the article Optimality of Syntactic Dependency Distances. This is the first release of the Optimality of Syntactic Dependency Distances repository at Github.com. The sole purpose
Carlos Gómez-Rodríguez +2 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Human Gene Functional Network-Informed Prediction of HIV-1 Host Dependency Factors
mSystems, 2020 Human immunodeficiency virus type 1 (HIV-1) depends on a class of host proteins called host dependency factors (HDFs) to facilitate its infection. So far experimental efforts have detected a certain number of HDFs, but the gene inventory of HIV-1 HDFs ...
Chen Fu +6 more
doaj +1 more source
Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
iScience, 2023 Summary: The noncoding genome presents a largely untapped source of new biological insights, including thousands of long noncoding RNA (lncRNA) loci. While lncRNA dysregulation has been reported in myeloid malignancies, their functional relevance remains
Michelle Ng +15 more
doaj +1 more source