Results 81 to 90 of about 5,517,155 (276)

Asymptotic behavior of solutions of a partial functional differential equation

Electronic Journal of Differential Equations, 2000
The asymptotic behavior of solutions of an asymptotically autonomous partial functional differential equation is investigated. The aim of the present paper is to extend our earlier result for ordinary functional differential equations and difference ...
Gyula Farkas
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Analytic Solutions of an Iterative Functional Differential Equation near Resonance

International Journal of Differential Equations, 2009
We investigate the existence of analytic solutions of a class of second-order differential equations involving iterates of the unknown function 𝑥(𝑧)+𝑐𝑥(𝑧)=𝑥(𝑎𝑧+𝑏𝑥(𝑧)) in the complex field ℂ. By reducing the equation with the Schröder transformation to
Tongbo Liu, Hong Li
doaj   +1 more source

The existence and Hyers–Ulam stability of solution for an impulsive Riemann–Liouville fractional neutral functional stochastic differential equation with infinite delay of order 1<β<2 $1<\beta<2$

Boundary Value Problems, 2019
This paper deals with the existence of solution for an impulsive Riemann–Liouville fractional neutral functional stochastic differential equation with infinite delay of order ...
Yuchen Guo, Xiao-Bao Shu, Yongjin Li, Fei Xu   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Differential Transform Algorithm for Functional Differential Equations with Time-Dependent Delays

Complexity, 2020
An algorithm using the differential transformation which is convenient for finding numerical solutions to initial value problems for functional differential equations is proposed in this paper.
Josef Rebenda, Zuzana Pátíková
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Design of partial differential equation hull surfaces using genetic algorithms

, 2005
The automatic generation of a range of flat-sided hull forms which satisfy constraints on various primary and secondary geometric parameters is considered. The curved section of each hull surface is generated using the Partial Differential Equation (PDE)
Lowe, Tim W.
core   +5 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

An ordinary integro-differential equation with a degenerate kernel and an integral condition

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016
We consider the questions of one value solvability of the nonlocal boundary value problem for a nonlinear ordinary integro-differential equation with a degenerate kernel and a reflective argument.
Tursun K Yuldashev
doaj   +1 more source