Results 71 to 80 of about 120,037 (263)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
On solutions of a certain nonlinear differential-difference functional equation [PDF]
Mathematica BohemicaWe investigate all the possible finite order entire solutions of the Fermat-type differential-difference functional equation $(Af(z))^2+R^2(z)(Bf^{(m)}(z+c)+Cf^{(n)}(z))^2=Q(z)$, where $m,n\in\mathbb{N}$, $A,B,C\in\mathbb{C}\setminus\{0\}$ and $R(z)$, $Q(
Rajib Mandal, Raju Biswas
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reducible functional differential equations
International Journal of Mathematics and Mathematical Sciences, 1985 This is the first part of a survey on analytic solutions of functional differential equations (FDE). Some classes of FDE that can be reduced to ordinary differential equations are considered since they often provide an insight into the structure of ...
S. M. Shah, Joseph Wiener
doaj +1 more source
Boundary Value Problems, 2019 This paper deals with the existence of solution for an impulsive Riemann–Liouville fractional neutral functional stochastic differential equation with infinite delay of order ...
Yuchen Guo +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Electronic Journal of Differential Equations, 2009 This article concerns the first-order functional differential equation $$ x'(z)=x(p(z)+bx'(z)) $$ with the distinctive feature that the argument of the unknown function depends on the state derivative.
Pingping Zhang
doaj
Oscillation Criteria for Second-Order Delay, Difference, and Functional Equations
International Journal of Differential Equations, 2010 Consider the second-order linear delay differential equation x′′(t)+p(t)x(τ(t))=0, t≥t0, where p∈C([t0,∞),ℝ+), τ∈C([t0,∞),ℝ), τ(t) is nondecreasing, τ(t)≤t for t≥t0 and limt→∞τ(t)=∞, the (discrete analogue) second-order difference equation Δ2x(n)+p(n)x(τ(
L. K. Kikina, I. P. Stavroulakis
doaj +1 more source