Results 51 to 60 of about 5,517,155 (276)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Adjoint systems and Green functionals for second-order linear integro-differential equations with nonlocal conditions

open access: yesElectronic Journal of Differential Equations, 2015
In this work, we generalize so called Green's functional concept in literature to second-order linear integro-differential equation with nonlocal conditions. According to this technique, a linear completely nonhomogeneous nonlocal problem for a second-
Ali Sirma
doaj  

A FLOQUET THEORY FOR FUNCTIONAL DIFFERENTIAL EQUATION [PDF]

open access: yesProceedings of the National Academy of Sciences, 1962
Introduction.-Let C denote the space of continuous functions from [-h, 01 into Rm, m-dimensional Euclidean spa.ce, h > 0, with the norm in C given by 111\ = max 1{(u) l, -h s, by x,(u) = x(t + u), -h s u s 0. With this notation (due to Hale4) and the above definitions, we may write the linear functional differential equation with periodic ...
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Initial value problems of fractional order Hadamard-type functional differential equations

open access: yesElectronic Journal of Differential Equations, 2015
The Banach fixed point theorem and a nonlinear alternative of Leray-Schauder type are used to investigate the existence and uniqueness of solutions for fractional order Hadamard-type functional and neutral functional differential equations.
Bashir Ahmad, Sotiris K. Ntouyas
doaj  

Analytic Solutions of an Iterative Functional Differential Equations Near Regular Points

open access: yesJournal of Applied Mathematics, 2013
The existence of analytic solutions of an iterative functional differential equation is studied when the given functions are all analytic and when the given functions have regular points.
Lingxia Liu
doaj   +1 more source

Representation and stability of solutions of systems of functional differential equations with multiple delays

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
This paper is devoted to the study of systems of nonlinear functional differential equations with time-dependent coefficients and multiple variable increasing delays represented by functions $g_i(t)
Michal Pospíšil
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Functional differential equations of third order

open access: yesElectronic Journal of Differential Equations, 2005
In this paper, we consider the third-order neutral functional differential equation with distributed deviating arguments. We give sufficient conditions for the oscillatory behavior of this functional differential equation.
Tuncay Candan, Rajbir S. Dahiya
doaj  

On the surjectivity conditions of a linear functional differential operator of the second order

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
Linear second-order functional differential equations without the Volterra condition are studied. Sufficient conditions for the everywhere solvability of the equation (surjectivity of the corresponding functional differential operator) are obtained in ...
Eugene Bravyi
doaj   +1 more source

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