Results 41 to 50 of about 5,517,155 (276)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Existence and uniqueness of a solution to a partial integro-differential equation by the method of lines

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2008
In this work we consider a partial integro-differential equation. We reformulate it a functional integro-differential equation in a suitable Hilbert space. We apply the method of lines to establish the existence and uniqueness of a strong solution.
Dhirendra Bahuguna, J. Dabas
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Existence of solutions for quasilinear random impulsive neutral differential evolution equation

open access: yesArab Journal of Mathematical Sciences, 2018
This paper deals with the existence of solutions for quasilinear random impulsive neutral functional differential evolution equation in Banach spaces and the results are derived by using the analytic semigroup theory, fractional powers of operators and ...
B. Radhakrishnan, M. Tamilarasi
doaj   +1 more source

On Nonautonomous Functional Differential Equations

open access: yesJournal of Mathematical Analysis and Applications, 1999
The author investigates the existence of an evolution family for the nonautonomous Cauchy problem \[ x'(t)= A(t) x(t),\quad 0\leq s\leq t\leq T,\quad x(s)= x, \] in a Banach space \(X\). Each \(A(t)\) is a linear operator on \(X\). The following result is obtained: Let \(X\), \(Y\), and \(D\) be Banach spaces, \(D\) densely and continuously imbedded in
openaire   +2 more sources

A STABILITY THEOREM FOR FUNCTIONAL-DIFFERENTIAL EQUATIONS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1963
A sufficient condition for the asymptotic stability of the trivial solution of a functional differential system is given which generalizes a result of \textit{J. P. Lasalle} [IRE Trans. Circuit Theory 7, 520--527 (1960), \url{http://dx.doi.org/10.1109/TCT.1960.1086720}]. The result is illustrated by means of an example.
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Convex Solutions of an Iterative Functional Differential Equation

open access: yesAnnales Mathematicae Silesianae
In this paper, by Schauder's fixed point theorem and the Banach contraction principle, we consider the existence, uniqueness, and stability of convex solutions of a nonhomogeneous iterative functional differential equation.
Li Lin Huang, Hou Yu Zhao
doaj   +1 more source

Stability theory for functional-differential equations [PDF]

open access: yesTransactions of the American Mathematical Society, 1979
We consider a system of functional differential equations x ′ (
openaire   +2 more sources

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