Results 41 to 50 of about 120,037 (263)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revista de Ciencias, 1996 We state a growth functional equation related with the Von Bertalanffy physiological differential ...
Carlos Julio Rodríguez B. +1 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Existence of solutions for quasilinear random impulsive neutral differential evolution equation
Arab Journal of Mathematical Sciences, 2018 This paper deals with the existence of solutions for quasilinear random impulsive neutral functional differential evolution equation in Banach spaces and the results are derived by using the analytic semigroup theory, fractional powers of operators and ...
B. Radhakrishnan, M. Tamilarasi
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A Partial Functional Differential Equation
Journal of Mathematical Analysis and Applications, 2001 The author of this interesting paper investigates the partial functional differential equation \[ \partial u(x,t)\partial t =k \partial^2 u(x,t)\partial x^2+ru(x,t-T)[1-u(x,t)], \;\;t\geq 0, \;\;x\in [{}0,\pi ]{} \] under the boundary condition \(u(0,t)=u(\pi ,t)=0\) (\(t>0\)) and \(u(x,s)=\phi (x,s)\), \(-T\leq s\leq 0\), \(0\leq x\leq \pi \).
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Stability theory for functional-differential equations [PDF]
Transactions of the American Mathematical Society, 1979 We consider a system of functional differential equations x ′ (
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Electronic Journal of Qualitative Theory of Differential Equations, 2008 In this work we consider a partial integro-differential equation. We reformulate it a functional integro-differential equation in a suitable Hilbert space. We apply the method of lines to establish the existence and uniqueness of a strong solution.
Dhirendra Bahuguna, J. Dabas
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A FLOQUET THEORY FOR FUNCTIONAL DIFFERENTIAL EQUATION [PDF]
Proceedings of the National Academy of Sciences, 1962 Introduction.-Let C denote the space of continuous functions from [-h, 01 into Rm, m-dimensional Euclidean spa.ce, h > 0, with the norm in C given by 111\ = max 1{(u) l, -h s, by x,(u) = x(t + u), -h s u s 0. With this notation (due to Hale4) and the above definitions, we may write the linear functional differential equation with periodic ...
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