Results 51 to 60 of about 5,539,774 (289)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Uniform Persistence in Functional Differential Equations
, 1995 In this paper, we investigate the question of uniform persistence for retarded functional differential equations. By utilizing Liapunov-like functions, Razumikhin techniques, and differential inequalities, we are able to establish criteria for uniform ...
Ruan, S.G, Freedman, H.I
core +1 more source
On functional differential equations associated to controlled structures with propagation
Electronic Journal of Qualitative Theory of Differential Equations, 2016 The method of integration along the characteristics has turned to be quite fruitful for qualitative analysis of physical and engineering systems described by large classes of partial differential equations of hyperbolic type in the plane (time and one ...
Vladimir Rasvan
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
On Nonautonomous Functional Differential Equations
Journal of Mathematical Analysis and Applications, 1999 The author investigates the existence of an evolution family for the nonautonomous Cauchy problem \[ x'(t)= A(t) x(t),\quad 0\leq s\leq t\leq T,\quad x(s)= x, \] in a Banach space \(X\). Each \(A(t)\) is a linear operator on \(X\). The following result is obtained: Let \(X\), \(Y\), and \(D\) be Banach spaces, \(D\) densely and continuously imbedded in
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A STABILITY THEOREM FOR FUNCTIONAL-DIFFERENTIAL EQUATIONS [PDF]
Proceedings of the National Academy of Sciences, 1963 A sufficient condition for the asymptotic stability of the trivial solution of a functional differential system is given which generalizes a result of \textit{J. P. Lasalle} [IRE Trans. Circuit Theory 7, 520--527 (1960), \url{http://dx.doi.org/10.1109/TCT.1960.1086720}]. The result is illustrated by means of an example.
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Stability theory for functional-differential equations [PDF]
Transactions of the American Mathematical Society, 1979 We consider a system of functional differential equations x ′ (
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source