Results 71 to 80 of about 5,539,774 (289)

Asymptotic Comparison of the Solutions of Linear Time-Delay Systems with Point and Distributed Lags with Those of Their Limiting Equations

open access: yesAbstract and Applied Analysis, 2009
This paper investigates the relations between the particular eigensolutions of a limiting functional differential equation of any order, which is the nominal (unperturbed) linear autonomous differential equations, and the associate ones of the ...
M. De la Sen
doaj   +1 more source

The Coercivity of Functional Differential Equations

open access: yesJournal of Mathematical Sciences, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Asymptotic behavior of solutions of a partial functional differential equation

open access: yesElectronic Journal of Differential Equations, 2000
The asymptotic behavior of solutions of an asymptotically autonomous partial functional differential equation is investigated. The aim of the present paper is to extend our earlier result for ordinary functional differential equations and difference ...
Gyula Farkas
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Oscillation criteria for functional differential equations

open access: yesElectronic Journal of Differential Equations, 2005
Consider the first-order linear delay differential equation $$ x'(t)+p(t)x(au (t))=0,quad tgeq t_{0}, $$ and the second-order linear delay equation $$ x''(t)+p(t)x(au (t))=0,quad tgeq t_{0}, $$ where $p$ and $au $ are continuous functions on $[t_{0 ...
Ioannis P. Stavroulakis
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Exponential Dichotomies, the Fredholm Alternative, and Transverse Homoclinic Orbits in Partial Functional Differential Equations

open access: yes, 2005
In this paper we investigate the transversality of homoclinic orbits in partial functional differential equations. We first discuss the exponential dichotomies for linear operator equations.
Ruan, Shigui, Zhang, Weinian
core   +1 more source

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