Results 161 to 170 of about 328,126 (218)

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Relationship between long covid and functional disability in adults and the seniors in the south of Brazil. [PDF]

BMC Public Health
Vieira YP, da Silva LN, Nunes BP, Gonzalez TN, Duro SMS, de Oliveira Saes M.   +5 more
europepmc   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

Functional disability mediates the relationship between pain severity and quality of life in pregnant women with pregnancy-related low back pain: a moderated mediation analysis. [PDF]

BMC Pregnancy Childbirth
Chang YW, Chou FH.
europepmc   +1 more source

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

Advanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu, Guanming Lin, Xiaohui Hong, Chuting Liu, Xinyi Qu, Kangjian Jiao, Lei Zhang, Bingzhe Xu, Jun Yan, Yancong Qiao, Xudong Lin   +10 more
wiley   +1 more source

Association between community-based resource collection site use and functional disability risk among older adults: A Quasi-experimental study. [PDF]

PLoS One
Abe N, Ide K, Kawaguchi K, Kumazawa D, Kondo K.   +4 more
europepmc   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Food and Water Insecurity and Functional Disability in Adults.

JAMA Netw Open
Wang Y, Armijos RX, Commodore S, Bidulescu A, Weigel MM.   +4 more
europepmc   +1 more source

Exploring the relationship between temperament traits, psychological symptoms, and functional disability assessed with the WHODAS 2.0 in persons with multiple sclerosis. [PDF]

Front Neurol
Infortuna C, Buccafusca M, Graceffa AMS, Maiorana E, Wang R, Ganesh S, Yedidia O, Bruno A, Iannuzzo F, Thomas FP, Battaglia F.   +10 more
europepmc   +1 more source