Results 41 to 50 of about 796,111 (314)

Ethnic Differences in Disability Prevalence and Their Determinants Studied over a 20-Year Period: A Cohort Study. [PDF]

, 2012
BACKGROUND: To compare disability prevalence rates in the major ethnic groups in the UK and understand the risk factors contributing to differences identified.
Baradaran, Hamid Reza, Chaturvedi, Nishi, Forouhi, Nita G., Tillin, Therese, Whincup, Peter, Williams, Emily   +5 more
core   +8 more sources

Association of frailty with cognitive impairment and functional disability in older adults with affective disorders: a brief research report

Frontiers in Psychiatry, 2023
IntroductionThe Clinical-Functional Vulnerability Index (IVCF-20) is a validated multidimensional instrument that has been used in Brazil to evaluate functional disability in frail older adults. The main aim of this study was to assess frailty using this
Ariane M. Monteiro, Marcus K. Borges
doaj   +1 more source

Trajectories of functional disability for the elderly in Britain [PDF]

, 2015
This study uses an innovative approach to characterise trajectories of functional disability over the final stages of the life course. We use data from the British Household Panel Survey (BHPS), an annual household survey of all adults in a ...
French, Robert, Steele, Fiona
core   +5 more sources

Does My Stigma Look Big in This? Considering the acceptability and desirability in the inclusive design of technology products [PDF]

, 2007
This paper examines the relationship between stigmatic effects of design of technology products for the older and disabled and contextualizes this within wider social themes such as the functional, social, medical and technology models of disability ...
A. Busch, A. Newell, B. Gleeson, C. McCredie, D. Miller, E. Goffman, J. Cassim, M. Oliver, R. Imire, V. Finkelstein   +9 more
core   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Development of a first-contact protocol to guide assessment of adult patients in rehabilitation services networks [PDF]

, 2016
OBJECTIVE: This paper describes the development of the Protocol for Identification of Problems for Rehabilitation (PLPR), a tool to standardize collection of functional information based on the International Classification of Functioning, Disability and ...
Coster, Wendy J., César, Cibele C., Ferreira, Fabiane R., Furtado, Sheyla R.C., Mancini, Marisa C., Sampaio, Rosana F., Souza, Mariana A.P.   +6 more
core   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Relationship between Stressors and Pain-Related Clinical Outcomes in Pediatric Chronic Pain Patients

Children, 2021
Youth with chronic pain and youth who have experienced stressors are at risk for poor outcomes; however, little is known about the intersection of pain and stressors. This study aims to understand the prevalence of stressors among youth with chronic pain
Anjana Jagpal, Keri Hainsworth, Ratka Galijot, Katherine S. Salamon, Kim Anderson Khan, Susan T. Tran   +5 more
doaj   +1 more source

Long-term Symptomatic, Functional, and Work Outcomes of Carpal Tunnel Syndrome among Construction Workers [PDF]

, 2016
BACKGROUND: The long-term outcomes of carpal tunnel syndrome (CTS) including symptoms, functional status, work disability, and economic impact are unknown. METHODS: We conducted a retrospective study of 234 active construction workers with medical claims
Amick, Armstrong, Cagle, Dale, Daniell, Daniell, DeStefano, Dong, Foley, Forde, Franklin, Franzblau, Gardner, Gardner, Gimeno, Glazner, Gorsche, Hudak, Ilmarinen, Katz, Keith, Kuorinka, Levine, Lipscomb, Louie, Manktelow, Padua, Pensy, Probst, Resende, Rosecrance, Salerno, Spector, Turner, Ware, Welch, Wellman   +36 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source