Results 81 to 90 of about 328,126 (218)

Effects of Active Video Games Combined with Conventional Physical Therapy on Perceived Functionality in Older Adults with Knee or Hip Osteoarthritis: A Randomized Controlled Trial

Applied Sciences
Background: Osteoarthritis (OA) leads to functional decline in older adults. This study aimed to evaluate the effectiveness of active video games (AVGs) as a complement to conventional physical therapy (CPT) in improving functional disability.
Francisco Guede-Rojas, Cristhian Mendoza, Jorge Fuentes-Contreras, Cristian Alvarez, Bárbara Agurto Tarbes, Javiera Karina Muñoz-Gutiérrez, Adolfo Soto-Martínez, Claudio Carvajal-Parodi   +7 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records From an Integrated Health System

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the frequency and timing of physician referrals to physical therapists (PTs) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source

Editorial: Impacts of common geriatric syndromes and their interaction with chronic diseases on health

Frontiers in Medicine, 2022
Jinhui Wu, Jinhui Wu, Lin Kang, Ming Yang, Ming Yang, Andrea P. Rossi   +5 more
doaj   +1 more source

Functional Profile Differences Across Diagnostic Categories Using WHODAS 2.0 in Adults with Neurological, Musculoskeletal, and Chronic Pain Conditions

Journal of Functional Morphology and Kinesiology
Background: Functional disability is a growing concern in aging populations with chronic health conditions, yet few studies have compared disability profiles across diagnostic categories using standardized tools.
Patricio Barria, Asterio Andrade, Bessié Córdova Albayay, Felipe Covarrubias-Escudero, Carlos Cifuentes, Juan Camilo Moreno, Juan Pablo Appelgren-González   +6 more
doaj   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Cross-cultural adaption of the German Quebec Back Pain Disability Scale: an exposure-specific measurement for back pain patients

Journal of Pain Research, 2016
Jenny Riecke,1 Sebastian Holzapfel,1 Winfried Rief,1 Harald Lachnit,2 Julia A Glombiewski1 1Department for Clinical Psychology and Psychotherapy, 2Department for Associative Learning, University of Marburg, Marburg, Germany Study design: Cross-cultural ...
Riecke J, Holzapfel S, Rief W, Lachnit H, Glombiewski JA   +4 more
doaj  

The financial toxicity of ageing: a longitudinal analysis of the health and functional determinants of household OOP spending in rural South Africa

Frontiers in Public Health
BackgroundIn sub-Saharan Africa, the epidemiological transition has created a double burden of chronic disease and functional decline. While the relationship between non-communicable diseases (NCDs) and out-of-pocket (OOP) health expenditure is well ...
Lawrence Ejike Ugwu, Lawrence Ejike Ugwu, Janine Anthea White, Matthew Aplin-Houtz, Erhabor Sunday Idemudia   +4 more
doaj   +1 more source

Financial Distress and Its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

Predictors of methotrexate adherence and patient's awareness of it in rheumatoid arthritis and its effect on quality of life

Journal of Pharmaceutical Policy and Practice
Introduction Adherence studies among rheumatoid arthritis (RA) patients, in Egypt and throughout the Middle East region, are lacking. This study aimed to evaluate methotrexate (MTX) adherence in Rheumatoid arthritis (RA) patients and to identify specific
Marwa Mohamed Abd El-Maboud, Heba F. Salem, Mohamed N. Salem, Mahmoud Abo Elmaaty, Nermin Eissa, Amira S. A. Said, Raghda R. S. Hussein   +6 more
doaj   +1 more source