Results 61 to 70 of about 5,382,530 (248)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Disease modeling in functional movement disorders

, 2014
INTRODUCTION: The mechanisms underlying functional movement disorders are poorly known. We examined whether experience of a movement disorder model in the family and/or the friendships contributes to functional movement disorders.
LIVREA, Paolo, Pellicciari R, Defazio G., Superbo M, Superbo, Maria, Defazio G, Defazio, Giovanni, PELLICCIARI, ROBERTA, Gigante AF, Gigante, Angelo Fabio, Livrea P   +10 more
core   +1 more source

Decomposition of Spontaneous Brain Activity into Distinct fMRI Co-activation Patterns

Frontiers in Systems Neuroscience, 2013
Recent fMRI studies have shown that analysis of the human brain’s spontaneous activity may provide a powerful approach to reveal its functional organization. Dedicated methods have been proposed to investigate co-variation of signals from different brain
Xiao eLiu, Catie eChang, Jeff H. Duyn
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Bloating and gas formation: modern opportunities for treatment

Лечащий Врач, 2021
Bloating is a subjective feeling of excessive gas formation and passage of gasses. It is more common in patients with gastrointestinal disorders. For therapy of disorders involving excessive gas formation, fermentative nutraceutical containing alpha ...
L. I. Butorova, N. G. Kadnikova, M. A. Osadchuk, T. E. Plavnik, G. M. Tokmulina   +4 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Evaluation of functional disorders in tuberculosis patients with the severe course of the disease

Туберкулез и болезни лёгких, 2020
The objective: to assess functional disorders in various models of clinical situations in patients with the severe course of tuberculosis.Subjects and methods. Functional disorders were assessed in 154 tuberculosis patients (HIV positive or HIV negative)
T. V. Pyanzova, I. A. Vasilyeva, Yu. T. Dzhangildin   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Decoding IBS: a machine learning approach to psychological distress and gut-brain interaction

BMC Gastroenterology
Purpose Irritable bowel syndrome (IBS) is a diagnosis defined by gastrointestinal (GI) symptoms like abdominal pain and changes associated with defecation.
Astri J. Lundervold, Julie E. Billing, Birgitte Berentsen, Gülen A. Lied, Elisabeth K. Steinsvik, Trygve Hausken, Arvid Lundervold   +6 more
doaj   +1 more source