The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Bahariya Formation of the northern Western Desert, Egypt, is well-known for its plentiful and diverse vertebrate fossil assemblages, especially dinosaurs, and also eminent for its rich fossil macroflora.
Clément Coiffard +3 more
doaj +1 more source
Does functional soil microbial diversity contribute to explain within-site plant beta-diversity in an alpine grassland and a dehesa meadow in Spain? [PDF]
Questions: Once that the effects of hydrological and chemical soil properties have been accounted for, does soil microbial diversity contribute to explain change in plant community structure (i.e. within-site beta-diversity)?
Araya, Yoseph N. +4 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Complex dynamics in coevolution models with ratio-dependent functional response
We explore the complex dynamical behavior of two simple predator-prey models of biological coevolution that on the ecological level account for interspecific and intraspecific competition, as well as adaptive foraging behavior.
Bascompte +48 more
core +1 more source
The Earth Microbiome Project: Meeting report of the "1 EMP meeting on sample selection and acquisition" at Argonne National Laboratory October 6 2010. [PDF]
This report details the outcome the first meeting of the Earth Microbiome Project to discuss sample selection and acquisition. The meeting, held at the Argonne National Laboratory on Wednesday October 6(th) 2010, focused on discussion of how to ...
Docherty, Kathryn +17 more
core +3 more sources
Diverse functions of perineuronal nets
Perineuronal nets represent well-organised components of the extracellular matrix, which are surrounding cell bodies, dendrites, and axon segments of a particular class of neurones as well as forming lattice-like structures. The role of perineuronal nets is not fully elucidated yet.
Magdalena, Karetko +1 more
openaire +2 more sources
Functional diversity promotes phytoplankton resource use efficiency
Understanding the relationship between biodiversity and ecosystem functioning (BEF) is a central topic in ecology. Multi‐trait–based functional diversity has been proposed to improve mechanistic understanding of the BEF relationship; however, how trait ...
L. Ye +5 more
semanticscholar +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Exotic species invasions undermine regional functional diversity of freshwater fish
Exotic species invasions often result in native biodiversity loss, i.e. a lower taxonomic diversity, but current knowledge on invasions effects underlined a potential increase of functional diversity.
M. Milardi +3 more
semanticscholar +1 more source

