Results 151 to 160 of about 614,127 (218)

Taxonomic and functional diversity of the microbiome associated with the freshwater sponge Metania sp. (Haplosclerida: Metaniidae) from the Brazilian Cerrado, a metagenomic approach. [PDF]

BMC Microbiol
Alves CPP, Pinto OHB, Pappas GJ, Mota SS, Rahlff J, Krüger RH.   +5 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Functional diversity of soil microbial communities increases with ecosystem development. [PDF]

Nat Commun
Sveen TR, Viketoft M, Bengtsson J, Strengbom J, Lejoly J, Buegger F, Pritsch K, Fritscher J, Hildebrand F, Osburn E, Hannula SE, Bahram M.   +11 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Asynchrony and functional diversity couple herbivore community dynamics to host plant diversity. [PDF]

Nat Commun
Wang MQ, Albert G, Seifert CL, Chesters D, Bruelheide H, Li Y, Chen JT, Davrinche A, Haider S, Li S, von Oheimb G, Proß T, Ma K, Liu X, Luo A, Schuldt A, Zhu CD.   +16 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Land-use change undermines the stability of avian functional diversity. [PDF]

Nature
Weeks TL, Walkden PA, Edwards DP, Lees AC, Pigot AL, Purvis A, Tobias JA.   +6 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Functional diversity of Brazilian bees: revealing the unique patterns of the Neotropics. [PDF]

Oecologia
Cordeiro GD, Giannini TC, Consorte PM, Costa ACJ, Machida WS, Marques BF, Mazzei ND, Menezes PP, Resende LS, Shimoda JA, Souza RS, Acosta AL, Aguiar AJC, Almeida EAB, Alves DA, Alves-Dos-Santos I, Andrade TO, Anjos-Silva EJ, Barbosa AS, Barbosa ERM, Bezerra LA, Borges RC, Brito TF, Camacho GP, Campbell AJ, Castro MS, Coelho BWT, Ferrari RR, Garófalo CA, González-Chaves AD, Keller GO, Lichtenberg EM, Marshall L, Martínez-Martínez CA, Martins MB, Martins AC, Maués MM, Moleiro HP, Mouga DMDS, de Oliveira FF, Ramos KS, Ramos RL, Rocha-Filho LC, Santos IPV, Santos S, Santos Júnior JE, Shibata A, Silva DP, Sousa FG, Teixeira CMN, Tietz AL, Trindade-Santos ME, Vilhena PS, Vivallo F, Carvalheiro LG.   +54 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source