Results 51 to 60 of about 191,132 (268)
On the number of transversals in random trees [PDF]
Discrete Mathematics & Theoretical Computer Science, 2012 We study transversals in random trees with n vertices asymptotically as n tends to infinity. Our investigation treats the average number of transversals of fixed size, the size of a random transversal as well as the probability that a random subset of ...
Bernhard Gittenberger, Veronika Kraus
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Reciprocal Convex Costs for Ratio Matching: Axiomatic Characterization
AxiomsWe study ratio-induced mismatch cost functions of the form c(s,o)=JιS(s)/ιO(o) built from positive scale maps ιS:S→R>0 and ιO:O→R>0 and a penalty J:(0,∞)→[0,∞).
Jonathan Washburn, Amir Rahnamai Barghi
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
On a Functional-Equation of A. Hurwitz
Advances in Mathematics, 1995 The paper deals with the equation \((*)\) \(G'(z) = 2 \pi ie^{2 \pi iz} G(z + 1)\) and its adjoint equation \(F'(z) = - 2 \pi ie^{2 \pi iz} F(z - 1)\) in the complex domain. It is shown that \(G_ 0(z) = \int e^{-2 \pi iuz + \pi iu^ 2} \Gamma (u) du\) and \(F_ 0(z) = \int e^{2 \pi izu - \pi iu^ 2} \Gamma^{-1} (1 + u) du\) with integration over suitable ...
Berenstein, C.A., Sebbar, A.
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
On the Generalized Stabilities of Functional Equations via Isometries
AxiomsThe main goal of this research article is to investigate the stability of generalized norm-additive functional equations. This study demonstrates that these equations are Hyers-Ulam stable for surjective functions from an arbitrary group G to a real ...
Muhammad Sarfraz +3 more
doaj +1 more source