Results 141 to 150 of about 58,526 (297)
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Mathematical models of health focusing on diabetes: Delay differential equations and data mining [PDF]
Mathematical models have been applied to biology and health to gain a better understanding of physiological systems and disease, as well as to improve levels of treatment and care for certain conditions.
Easton, Jonathan
core
Curves in the Minkowski plane and Lorentzian surfaces [PDF]
, 2012 We investigate in this thesis the generic properties of curves in the Minkowski plane R2 1 and of smooth Lorentzian surfaces. The generic properties of curves in R2 1 are obtained by studying the contacts of curves in R2 1 with lines and pseudo-circles ...
SALOOM, AMANI
core
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
On Solutions of Some Functional Equations of Radical Type [PDF]
Many authors have studied various functional equations of forms patterned on the equation expressed as ga2+b2=g(a)+g(b), which can be considered, e.g., for real functions.
Janusz Brzdęk
core +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Harnack-Ungleichungen und Anwendungen auf stochastische Gleichungen [PDF]
, 2009 Ouyang S-X. Harnack inequalities and applications for stochastic equations. Bielefeld (Germany): Bielefeld University; 2009.In dieser Dissertation studieren wir hauptsächlich Wangs Harnack-Ungleichungen und ihre Anwendungen auf Übergangshalbgruppen, die ...
Ouyang, Shun-Xiang
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source