Results 71 to 80 of about 3,720,701 (268)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Removal of Paralytic Shellfish Toxins by Probiotic Lactic Acid Bacteria

Toxins, 2014
Paralytic shellfish toxins (PSTs) are non-protein neurotoxins produced by saltwater dinoflagellates and freshwater cyanobacteria. The ability of Lactobacillus rhamnosus strains GG and LC-705 (in viable and non-viable forms) to remove PSTs (saxitoxin (STX)
Mari Vasama, Himanshu Kumar, Seppo Salminen, Carolyn A. Haskard   +3 more
doaj   +1 more source

The Development of New Functional Foods and Ingredients

Functional foods have emerged as a crucial area of research and innovation in the realm of food science, offering promising solutions for the prevention and management of chronic diseases such as cardiovascular disease, cancer, osteoporosis, diabetes ...
Mi Jeong Kim, Jeung Hee Lee, Choon Young Kim   +2 more
core   +1 more source

Tropical foods as functional foods for metabolic syndrome

, 2020
du Preez, R ORCiD: 0000-0003-2164-0819Tropical foods are an integral part of the traditional diet and form part of traditional medicine in many countries.
Lindsay Brown, du Preez, Ryan, OD John (9865283), Panchal, Sunil K, Panchal, Sunil K. (R20071), Ryan du Preez, Sunil K. Panchal, L Brown (9865289), Panchal, Sunil K., SK Panchal (9865286), John, Oliver D, Brown, Lindsay, John, Oliver D., Oliver D. John, Ryan du Preez (9793616)   +14 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

FUNCTIONAL FOODS: CONSUMER ISSUES AND FUTURE CHALLENGES [PDF]

Scientific progress in understanding the relationship of diet to disease, along with increasing health-care costs and consumersÂ’' desires to make healthy lifestyle improvements, provides a significant impetus for the development of novel foods with ...
Singletary, Keith W., Morganosky, Michelle A.   +1 more
core  

Microencapsulation of fat-removing Lactobacillales and polyphenols from Theobroma cacao L. as a combined strategy for intestinal removal of free fatty acids evaluated by simulated in vitro digestion

Cocoa polyphenols and Lactobacillales have shown promising effects in mitigating the adverse health effects associated with high-fat diets by removing free fatty acids from the gastrointestinal tract.
Quintanilla-Carvajal M.X, Paola Rodriguez-Castaño G, Acosta-González A., Quiroz-Eraso S   +3 more
core   +1 more source

Fermentation of Foods and Beverages as a Tool for Increasing Availability of Bioactive Compounds. Focus on Short-Chain Fatty Acids

, 2020
Emerging evidence suggests that fermentation, historically used for the preservation of perishable foods, may be considered as a useful tool for increasing the nutritional value of fermented products, in terms of increases in bioactive compound content ...
Roberto Ciampaglia, Gian Carlo Tenore, Giuseppe Annunziata, Angela Arnone, Ettore Novellino   +4 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source