Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An Analysis of Variability in the Content of Phenolic Acids and Flavonoids in Camelina Seeds Depending on Weather Conditions, Functional Form, and Genotypes. [PDF]
Molecules, 2022 Kurasiak-Popowska D +4 more
europepmc +1 more source
DICHOTOMOUS-CHOICE, CONTINGENT-VALUATION QUESTIONS: FUNCTIONAL FORM IS IMPORTANT [PDF]
A variety of questioning formats have been used in contingent-valuation studies, with dichotomous-choice questions becoming the preferred format. However, as with any empirical technique, continued applications raise questions that require attention if ...
Boyle, Kevin J.
core
THE IMPLEMENTATION OF GRAMMATICAL FUNCTIONS IN FUNCTIONAL DISCOURSE GRAMMAR [PDF]
, 2007 underlying representation in a more or less across the board fashion, only taking into consideration the language dependent semantic function hierarchy.
Bakker, D. +5 more
core
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Is there a dose-response relationship? Investigating the functional form between COVID-19 incidence rates and life satisfaction in a multilevel framework. [PDF]
J Happiness Stud, 2022 Bittmann F.
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Localization and Functional Characterization of an Occipital Visual Word form Sensitive Area
Scientific Reports, 2018 In human occipitotemporal cortex, category-specific processing for visual objects seems to involve pairs of cortical regions, often with one located in the occipital cortex and another more anteriorly. We investigated whether such an arrangement might be
Bo Zhang, Sheng He, Xuchu Weng
doaj +1 more source
The Functional Form of the Relationship between Body Height, Body Mass Index and Change of Direction Speed, Agility in Elite Female Basketball and Handball Players. [PDF]
Int J Environ Res Public Health, 2022 Popowczak M +3 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source